摘要
目的分析广州地区2008年至2012年1 392 884例无偿献血标本传染性疾病的筛查结果,评估血液不合格的主要原因,为制定献血前血液筛查措施、减少血液资源浪费、保障血液安全提供科学依据。方法采用ELISA方法对广州市2008年至2012年无偿献血者血液标本进行检测,检测项目包括:ALT、HBsAg、抗-HCV、抗-HIV及抗-TP,对检测结果进行统计分析。结果广州地区2008年至2012年无偿献血者总阳性率为4.35%,各检测项目不合格率分别为:ALT:2.23%,HBsAg:0.9%,抗-HCV:0.54%,抗-TP:0.52%,抗-HIV:0.16%。各年间阳性率差异有统计学意义(P<0.05)。结论广州地区无偿献血标本检测不合格项目中ALT阳性率最高,总不合格率在近两年呈下降趋势。应进一步加大无偿献血宣传力度,加强献血前快速筛查的灵敏度及献血者传染性疾病相关指标检测水平,从低危人群中招募无偿献血者,从而更有效地减少血液报废率和保障血液安全。
Objective By screening 1 392 884 samples of blood donation in Guangzhou from 2008 to 2012 for infectious diseases, and appraising the main reason of blood disqualification, a scientific basis will be provided to establish blood screening measures, reduce blood resource wasting and guarantee the blood safety. Methods The samples were tested by ELISA, test items including ALT, HbsAg, anti-HCV, anti-HIV and anti-TP, and the result was analysed. Results The blood donors＇ total positive rate was 4.35%; the unqualified rate of each item was： ALT （2.23%） 〉 HBsAg （0.9%）〉 anti-HCV （0.54% ）〉 anti-TP（0.52%）〉 anti-HIV （0.16% ）. The the positive rate had statistically significant difference between the years （P 〈0.05）. Conclusions In Guangzhou, the positive rate of ALT is the highest, and the total positive rate has declined in the recent two years. The publicity of blood donation should be further strengthened, the blood screening level raised, and blood donors recruited from low-risk population, so as to effectively reduce blood wasting rate and guarantee blood safety.
出处
《临床医学工程》
2014年第4期530-531,534,共3页
Clinical Medicine & Engineering
基金
广州市医药卫生科技项目(2013A011122)
关键词
无偿献血
血液检测
传染性标志物
Voluntary blood donation
Blood detection
Infectious markers
