摘要
目的 :探讨如何提高对早期胃癌的诊断率。方法 :回顾性分析了 1996年～ 1998年间 95 0 9例胃镜检查及2 2 78例病理活检资料 ,结合手术记录。结果 :有症状患者胃癌的检出率为 6.77% ( 64 4 / 95 0 9例 ) ,其中≥ 40岁者( 9 97% )明显高于 <40岁者 ( 1 0 8% ) (P <0 0 1)。男性高于女性 (P <0 .0 1)。病理活检中胃癌的检出率达 2 8.2 7%( 64 4 / 2 2 78例 ) ,胃癌及癌前病变的病理检出总的阳性率高达 70 .85 % ( 1614 / 2 2 78例 ) ,其中 <40岁患者的阳性率为 43.47% ,而≥ 40岁者则高达 75 .86% (P <0 .0 1)。胃癌及癌前病变的平均年龄均高于炎症组 (P <0 .0 1)。胃癌高发年龄为5 0～ 69岁之间 ,占 68.2 %。各病变中男性均多于女性 ,但 40岁以前胃癌中女性多于男性 (P <0 .0 5 )。胃体及贲门部位的恶性病变多于良性病变 (P <0 .0 1)。结论 :40岁以上有症状者应常规行胃镜检查 ,尤其是 5 0岁以上男性有癌前病变者以及胃体、贲门部位病变应常规行胃镜下病理活检 ,以及定期复查胃镜。
Purpose: The aim of this study was to enhance the diagnostic rate in early gastric cancer. Methods: 9 509 cases gastroscopy and 2 278 cases histopathology combining with the operation between 1996 and 1998 were analyzed retrospectively. Results: The detected rate of gastric cancer in the symptomatic patients is 6.77%(664/9509 cases), and the patients no younger than 40(9.97%) is more than that younger then 40(1.08%)(P<0.01), in which the male (8.42%) is more higher than the female (4.49%)(P<0.01). The detected rate of histopathology in gastric cancer is 28.27%(644/2278 cases). The total positive rate of histopathology (include gastric cancer and premalignant lesions) is 70.85%(1614/2278cases), in which, the positive rate of patients in age of less than 40 is 43.47%, but that in age of no less than 40 is 75.86%(P<0.01). The mean ages of patients with gastric cancer and premalignant lesions were older than that of patients with inflammation respectively (P<0.01). The peak incidence was in patients 50～69 years of age and accounted for 68.2%. The male is more than female in all lesions, but in patients with gastric cancer in age of less than 40, the female is more than the male (P<0.05). Malignant lesions in gastric body and cardia were more than benign lesion(P<0 01). Conclusion: The patients in age of more than 40 should be taken gastroscopy co mmonly, especially the male in age of more than 50, and with pre malignant lesions and the lesions in gastric body and cardia must be taken histopathology under gastroscope and follow up regularly.
出处
《临床消化病杂志》
2001年第1期12-15,共4页
Chinese Journal of Clinical Gastroenterology
关键词
胃癌
癌前病变
胃镜
Gastric cancer Premalignant lesion Gastroscope
