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两亲性纤维素接枝共聚物的合成及其在药物传递中的应用 被引量:2

Synthesis of Amphiphilic Cellulose Graft Copolymers and Their Applications in Drug Delivery
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摘要 目前,两亲性纤维素接枝共聚物及其自组装纳米粒作为一种新型的功能材料引起了制浆造纸、材料、生物医药等领域研究者的广泛兴趣。两亲性纤维素胶束作为新一代功能性的纳米材料,可以由两亲性纤维素接枝共聚物在水溶液中自组装得到。这类材料不仅可提高生物质资源的利用率,而且有望为生物质资源的高值化提供新的出口。本文主要从两亲性纤维素接枝共聚物的制备出发,旨在介绍纤维素基胶束的制备及其在药物传递方面的应用,并对其前景进行了合理的展望和预测。 Amphiphilic cellulose graft copolymers and their self-assembled nanoparticles have emerged as a novel generation of functional materials that attract much attention in broad fields, e.g. pulp & paper making, biological medicine, materials, and so on. Amphiphilic cellulose micelles can be conveniently prepared by self-assembly of amphiphilic cellulose graft copolymers in aqueous solution. These materials show promise to solve the problem con- cerning the depletion of non-renewable resources, and will improve the value-added utilization of biomass re- sources. In this paper, the cutting-edge researches on the preparation and application of amphiphilic cellulose graft copolymers are introduced, and the potential research in this field in future is anticipated.
出处 《造纸科学与技术》 北大核心 2014年第1期39-43,共5页 Paper Science & Technology
基金 国家自然科学基金项目(51103046)
关键词 两亲性纤维素 胶束 自组装 药物传递 amphiphilic cellulose micelles self-assembly drug delivery
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