摘要
过氧化物酶体增殖激活受体是一类与调节体内糖脂代谢,改善胰岛素抵抗密切相关的受体。而计算机辅助药物分子设计越来越成为新药开发领域重要的研究热点,它的发展和应用,大大提高了药物设计和新药开发的效率。本文将对计算机辅助药物分子设计在抗糖尿病PPARs调节剂方面的应用及研究进展加以综述。
Peroxisome proliferator-activated receptors are a series of receptors related to metabolism of sugar and lipid and amelioration of insulin resistance. On the other hand, Computer-aid drug design has become the hot spot in the research of new drug design. Its appearance and development has greatly improvd the efficiency of development of new drug. Application and progress in Computer-aid Drug Design on PPARs regulators are summarized in this article.
出处
《武警后勤学院学报（医学版）》
CAS
2014年第1期73-79,共7页
Journal of Logistics University of PAP（Medical Sciences）
