摘要
目的探讨血清胱抑素c的变化对妊娠高血压综合征患者的临床意义。方法分别检测70例妊娠高血压综合征患者及70例正常孕妇的血清胱抑素c、血肌酐、血尿素氮以及血尿酸等指标，并进行对比分析。结果妊娠高血压综合征患者各项指标均显著高于正常对照组（P〈0．01）。妊娠高血压综合征患者中，轻度组与中度组上述四项指标比较差异均无统计学意义（P〉0．05），而轻度组与中度组上述指标均显著低于重度组（P〈0．01）。结论血清胱抑素c的变化能够反映妊娠高血压综合征患者肾功能损害程度，可作为妊娠高血压综合征患者早期肾功能损伤的客观指标。
Objective To investigate the clinical significance of the changes of serum cystatin C in patients with pregnancy induced hypertension syndrome. Methods The levels of serum cystatin C, serum creatinine, blood urea nitrogen and serum uric acid were detected in 70 patients with pregnancy in duced hypertension syndrome and 70 normal pregnant women. And the results were given comparative a nalysis respectively. Results The levels of serum eystatin C, serum ereatinine, blood urea nitrogen, and serum uric acid in the pregnancy induced hypertension syndrome group were significantly higher than those in the normal control group（P 〈 0.01 ）. There were no significant differences between the moderateand mild pregnancy syndrome group about levels of these indexes induced hypertension these indexes. But the were significantly lowerin the mild group and the moderate group than those in the severe group（P 〈 O. O1 ）. Conclusions Chan ges of serum cystatin C in patients with pregnancy-induced hypertension can reflect the degree of renal dysfunction. Therefore, serum cystatin C can be used as an objective indicator of early renal injury in pa tients with pregnancy-induced hypertension.
出处
《中国实用医刊》
2014年第10期54-56,共3页
Chinese Journal of Practical Medicine
关键词
妊娠高血压综合征
血清胱抑素C
肾功能损伤
Pregnancy induced hypertension syndrome
Seram cystatin C
Renal impairment
