摘要
目的：探讨慢性阻塞性肺疾病（ COPD）评估测试（ CAT）在评估COPD患者临床预后中的应用价值。方法：将入选舟山市普陀区人民医院门诊COPD稳定期患者100例进行CAT评分和BODE指数评分，对两者结果做Spearman相关分析。记录3年随访患者病情急性加重次数和生存情况，并分析两种指标评估预后的差异。结果：CAT评分1、2、3和4级患者分别为28、30、29和13例，而根据BODE评分1、2、3和4级患者分别为31、29、28和12例。 CAT评分与BODE指数总分、4个变量得分均存在显著的相关性（ r＝-0．237、-0．772、0．789、-0．767、0．888，均P＜0．05）。多元回归分析结果显示CAT与BODE中的气流阻塞程度、呼吸困难程度、运动能力3个变量相关。随着CAT分级级别增加，COPD患者急性加重发作次数和病死率也相应增加两种指标在评估各级COPD患者急性加重发作次数之间差异无统计学意义（P＞0．05）；病死人数两者之间差异亦无统计学意义（1级：χ2＝0．919，2级：χ2＝0．001，3级：χ2＝0．177，4级：χ2＝0．322，均P＞0．05）。结论：CAT评分与BODE指数相关性较好，CAT适用于评价COPD患者生活质量，便于医师和患者简易快捷地了解病情，指导和监督治疗。
Objective： To evaluate the quality of life in patients with chronic＆nbsp;obstructive pulmonary disease （ COPD ） by COPD Assessment Test （ CAT ） and Body Mass Index , Airflow Obstruction , Dyspnea , Exercise Capacity Index （ BODE ） . Methods：One hundred patients with stable COPD admitted in Putuo People′s Hospital were recruited in the study .CAT and BODE index were measured for each patient .The deaths and frequency of exacerbations were recorded during 3-year follow-up period ,and the correlation between CAT and BODE in evaluating COPD prognosis was analyzed . Results：There were 28, 30, 29 and 13 patients with CAT score of 1, 2, 3 and 4, respectively;while there were 31, 29, 28 and 12 cases with BODE scores of 1, 2, 3 and 4.CAT scores were well correlated with BODE evaluation in terms of overall score and scores of 4 items （r=-0.237, -0.772, 0.789, -0.767, 0.888, respectively, Ps0.05）.Conclusion： CAT is relevant to BODE in evaluating incidence of exacerbation and mortality for patients with COPD and CAT is more easily to be applied .
出处
《浙江大学学报（医学版）》
CAS
CSCD
北大核心
2014年第2期207-211,共5页
Journal of Zhejiang University(Medical Sciences)
基金
舟山市科技计划(2011C13055)
关键词
肺疾病
慢性阻塞性
生活质量
预后
问卷调查
评价研究
Pulmonary disease,chronic obstructive
Quality of life
Prognosis
Questionnaires
Evaluation studies
