右美托咪定复合罗哌卡因对腋路臂丛神经阻滞的影响被引量：6

在线阅读下载PDF

导出

摘要目的:观察右美托咪定复合罗哌卡因对腋路臂丛神经阻滞的影响。方法:选择30例拟行前臂或手指手术的病人,随机分为两组,均在超声联合神经刺激仪引导下行腋路臂丛神经阻滞麻醉。D组(n=15)采用0.375%罗哌卡因+右美托咪定0.5μg/kg共29mL。R组(n=15)采用0.375%罗哌卡因29mL。观察项目:1术中生命征、Ramsay镇静评分;2神经阻滞情况;3术后镇痛情况。结果:D组感觉、运动阻滞维持时间及术后镇痛时间较R组延长(P<0.05),术后镇痛药使用较R组少(P<0.05)。D组3例患者阻滞后出现窦性心动过缓,余均无恶心、呕吐、低血压、呼吸抑制、局麻药中毒等不良反应。结论:0.5μg/kg的右美托咪定能增强罗哌卡因臂丛神经阻滞效果,延长术后镇痛时间,减少患者术后镇痛药物用量。

作者邱行林成新

机构地区广西医科大学第一附属医院麻醉科

出处《广西医科大学学报》 CAS 2014年第2期272-273,共2页 Journal of Guangxi Medical University

关键词臂丛神经阻滞右美托咪定罗哌卡因

分类号 R614 [医药卫生—麻醉学]

引文网络
相关文献

参考文献5

1Esmaoglu A,Yegenoglu F,Akin A,et al.Dexmedetomidine added to levobupivacaine prolongs axillary brachial plexus block[J] .Anesth Analg,2010,111:1 548-1 551.
2陈学丽,张晓奕,张华.超声引导下臂丛神经阻滞在上肢手术中的应用[J].临床麻醉学杂志,2011,27(8):775-776. 被引量：36
3Rancourt MP,Albert NT,Cote M,et al.Posterior Tibial Nerve Sensory Blockade Duration Prolonged by Adding Dexmedetomidine to Ropivacaine[J] .Anesth Analg,2012,115(4):958-962.
4Chad M,Brummett MD,Elizabeth K,et al.Perineural Dexmedetomidine Added to Ropivacaine for Sciatic Nerve Block in Rats Prolongs the Duration of Analgesia by Blocking the Hyperpolarization activated Cation Current[J] .Anesthesiology,2011,115:836-843.
5马浩南,李恒林,倪丽伟,邵菁菁.右美托咪定对罗哌卡因腋路臂丛神经阻滞时效的影响[J].临床麻醉学杂志,2012,28(6):531-533. 被引量：48

二级参考文献10

1Capdevila X, Biboulet P, Morau D, et al. How and why to use ultrasound for regional blockade. Acta Anaesthesiol Belg, 2008,59:147-154.
2Abrahams MS, Aziz MF, Fu RF, et al. Ultrasound guidance compared wish electrical neurostimulation for peripheral nerve block; a systematic review and meta-analysis of randomized controlled trials. Br J Anaesth, 2009,102:408-417.
3van Geffen GJ, van den BE, Brank GJ, et al. A prospective randomized trial of ultrasound guided versus nerve stimulation guided distal sciatic nerve block at the popliteal fossa. Anaesth Intensive Care, 2009,37 : 32-37.
4Carollo DS, Nossaman BD, Ramadhyani U. Dexmedetomi- dine: a review of clinical applications. Curr Opin Anaesthesi ol, 2008, 21(4): 457-461.
5王珊娟,蒋茹.局部麻醉药.杭燕南,主编.当代麻醉手册.上海:世界图书出版公司,2004:111-115.
6Chrysostomou C, Schmitt CG. Dexmedetomidine= sedation, analgesia and beyond. Expert Opin Drug Metab Toxicol, 2008, 4(5): 619-627.
7Kanazi GE, Aouad MT, Jabbou-Khoury SI, et al. Effect of low dose dexmedetomidine or clonidine on the characteristics of bupivacine spinal block. Acta Anaesth Stand, 2006, 50 (2) 222- 227.
8Venn RM, Bradshaw CJ, Spencer R, et al. Preliminary UK experience of dexmedetomidine, a novel agent for postopera- tive sedation in the intensive care unit. Anaesthesia, 1999, 54 (12): 1136-1142.
9胡宪文,张野,孔令锁,翁立军,蒋玲玲,李云.不同剂量右美托咪啶抑制气管插管诱发患者心血管反应效应的比较[J].中华麻醉学杂志,2010,30(11):1304-1306. 被引量：178
10梁永新,古妙宁,王世端,芦相玉.右美托咪定和丙泊酚用于硬膜外麻醉下妇科手术患者镇静的比较[J].临床麻醉学杂志,2011,27(4):376-378. 被引量：78