摘要
目的：研究肝硬化合并胆囊结石的相关因素并筛选危险因素，为临床防治提供参考。方法选择2011年5月～2013年3月我院收治的180例肝硬化患者，分为结石组和非结石组，分析两组一般资料、实验室检查和B超检查结果。结果结石组Child-Pugh分级较非结石组严重，饮酒率高于非结石组（P＜0.05），结石组血清总胆红素、内毒素、雌激素水平均显著高于非结石组（P＜0.05），结石组门静脉宽度、胆囊壁厚度均大于非结石组，腹水率高于非结石组（P＜0.05）。 Child-Pugh分级、内毒素、雌激素、腹水是肝硬化合并胆囊结石的危险因素（P＜0.05），危险度顺序由高到低为腹水、内毒素、雌激素、Child-Pugh分级。结论 Child-Pugh高分级、高浓度内毒素、雌激素及腹水是肝硬化患者发生胆囊结石的高危因素。
Objective To study related factors and risk factors of hepatocirrhosis with gallstone for the reference of pre-vention and treatment. Methods From May 2011 to March 2013 in our hospital 180 cases of patients with cirrhosis were selected and were divided into stones groups and non-stone group, the general information, laboratory tests, and B-test results were analyzed. Results The Child-Pugh classification, drink of stones group were serious higher than non-stone group （P〈0.05）, levels of serum total bilirubin, endotoxin, estrogen were significantly higher than non-calcu-lus group （P 〈0.05）, portal vein width, gallbladder wall thickness and ascites rate of stones groups were higher than non-stone group （P 〈0.05）. Child-Pugh classification, ET, E2, liver cirrhosis ascites were risk factors for gallbladder stones （P〈0.05）, in decreasing order of risk as ascites liked ET,E2, Child-Pugh classification. Conclusion Child-Pugh high grade, high concentrations of endotoxin, estrogen in patients with cirrhosis and ascites are risk factors for gall-stones.
出处
《中国现代医生》
2014年第14期1-3,7,共4页
China Modern Doctor
基金
国家自然科学基金(30973381)
关键词
肝硬化
门静脉高压
腹水
胆囊结石
危险因素
Hepatocirrhosis
Portal hypertension
Ascites
Gallstones
Risk factors
