摘要
目的观察外耳道高负压引流联合洛美沙星治疗慢性化脓性中耳炎的临床效果。方法将90例慢性化脓性中耳炎(单纯型)患者随机分为2组,观察组采用耳窥镜下外耳道高负压引流,同时联合洛美沙星滴耳液治疗,对照组只采用外耳道负压引流,比较两组患者临床疗效、致病菌清除率、听力改善情况。结果观察组患者总有效率为93.33%,明显高于对照组的66.67%(P<0.05);观察组致病菌清除率为86.67%,明显高于对照组的60%(P<0.05);观察组听力改善率为95.56%,明显高于对照组的82.22%(P<0.05);观察组不良反应发生率为17.77%,明显低于对照组的24.44%(P<0.05)。结论外耳道高负压引流联合洛美沙星用于单纯型慢性化脓性中耳炎的治疗,可提高临床疗效,改善听力情况,减少不良反应,值得临床推广应用。
Objective To observe the clinical effect of high suction drainage canal combined with lomefloxacin in treatment of chronic suppurative otitis media. Methods 90 chronic suppurative otitis media patients were randomly divided into two groups,observation group received high suction drainage canal combined with lomefloxacin under ear speculum,and control group only received high suction drainage canal. The clinical efficacy,pathogen clearance,listening improvement on of the two groups were compared. Results The total effective rate of observation group was 93. 33%,which was significantly higher than that of control group（66. 67%）（P ＆lt; 0. 05）. Pathogen clearance rate was 86. 67% in observation group,significantly higher than that in control group（60%）（ P ＆lt; 0. 05）. Hearing improvement was 95. 56% in observation group,significantly higher than that in control group（82. 22%）（ P ＆lt; 0. 05）.Incidence of adverse reactions was 17. 77% in observation group,significantly lower than that in control group（24.44%）（P ＆lt;0.05）. Conclusion High suction drainage canal combined with lomefloxacin can improve clinical outcomes,improve hearing,reduce adverse reactions for chronic suppurative otitis media,it is worthy of clinical application.
出处
《实用药物与临床》
CAS
2014年第5期629-631,共3页
Practical Pharmacy and Clinical Remedies
