摘要
目的：探讨喹硫平与利培酮治疗精神分裂症临床疗效的差异性。方法对喹硫平与利培酮治疗精神分裂症对照研究的5篇文献进行M eta分析。结果喹硫平组治疗前后自身对照显示，y合并＝2．85，95％ CI为（2．58，3．13）；治疗后组间临床疗效比较，d＝0．28，95％ CI 为（-0．03，0．59）；治疗第2周末组间阳性与阴性症状量表总分比较，y合并 ＝0．05，95％ C I为（-0．18，0．27）。结论喹硫平与利培酮治疗精神分裂症起效快，疗效均显著，总体疗效相当。
Objective To explore the difference between quetiapine and risperi-done in the treatment of schizophrenia .Methods Literatures of 5 control studies on quetiapine and risperi-done in the treatment of schizophrenia were analyzed by meta-analysis .Results Pre-and post-treatment self-control showed that ymerging =2 .85 ,95% CI was 2 .58~3 .13 in research group ;post-treatment group efficacy comparison showed that d=0 .28 ,95% CI was -0 .03~0 .59;at the end of 2nd week group com-parison of the PANSS total score showed that y merging =0 .05 ,95% CI was -0 .18~0 .27 .Conclusion Both quetiapine and risperidone take effect rapidly ,have an evident effect ,and their total efficacies are equiva-lent .
出处
《临床心身疾病杂志》
CAS
2014年第3期50-52,共3页
Journal of Clinical Psychosomatic Diseases
