摘要
目的探讨急性盆腔炎的发病特点、致病菌谱及抗菌药的治疗选择。方法采用回顾性分析的方法,选取我科2010年1月至2012年12月住院治疗的急性盆腔炎患者227例。结果 227例患者的平均年龄为(36.2±4.3)岁。主要临床症状包括下腹痛(219例,96.4%)、发热(183例,80.6%)、白带增多(92例,40.5%),其他伴随症状包括尿频尿急、恶心呕吐、腹胀腹泻等。182例(80.2%)患者联合应用抗生素,45例(19.8%)患者仅单独使用一种抗生素。在联合应用抗生素的患者中,使用二代头孢联合抗厌氧菌(甲硝唑)治疗73例(32.2%),使用三代头孢联合抗厌氧菌(甲硝唑)治疗85例(37.4%),使用喹诺酮类联合抗厌氧菌(甲硝唑)治疗24例(10.6%)。12例患者根据药敏实验结果更换敏感抗生素(厄他培南)。结论急性盆腔炎好发于育龄期女性,宫颈剧痛、子宫/附件区压痛、下腹部反跳痛是必要的体征,三代头孢在经验性治疗中可能优于二代头孢的选择,厄他培南对于难治性急性盆腔炎是优选替代药品。
Objective To explore the morbility characteristics,pathogenic bacterium spectrum and the selection of antibacterial agent of acute pelvic inflammatory. Methods A retrospective analysis of the clinical data of 227 patients who underwent acute pelvic inflammatory during January 2010 and December 2012 in Shengjing Hospital was carried out.Results In the 227 patients,the average ages were（ 36. 2 ± 4. 3） years old,the main clinical symptoms included hypogastralgia（ 219 cases,96. 4%）,febrile（ 183 cases,80. 6%）,leukorrhagia（ 92 cases,40. 5%）,and the urinary frequency and urgency,nausea and vomiting,abdominal distention diarrhea as the concomitant symptom. 182 cases（ 80. 2%） used the antibiotics in combination,45 cases（ 19. 8%） used one single antibiotics. In the patients who used the antibiotics in combination,there were 73 cases（ 32. 2%） used the second generation cephalosporin combined with anti-anaerobic agents（ Metronidazole）,and there were 85 cases（ 37.4%） used the third generation cephalosporin combined with anti-anaerobic agents（ Metronidazole）,and 24 cases（ 10. 6% %） used the quinolones combined with anti-anaerobic agents（ Metronidazole）. 12 cases replaced sensitive antibiotics on the basis of drug-sensitivity（ Ertapenem）. Conclusion Acute pelvic inflammatory occurs mainly in women in their reproductive years,cervical motion tenderness,the tenderness in uterus /attachment area,rebounded pain of lower abdomen are the necessary signs. The third generation cephalosporin is the optimization compared with the second generation cephalosporin,and Ertapenem is the preferred alternative medicine in refractory acute pelvic inflammatory disease.
出处
《实用药物与临床》
CAS
2014年第6期748-750,共3页
Practical Pharmacy and Clinical Remedies
关键词
急性盆腔炎
致病菌
药敏
治疗
Acute pelvic inflammatory disease
Pathogenic bacterium multicentre
Antibiotic sensitivity
