摘要
目的：观察改良颅内血肿微创清除术治疗脑出血的临床效果，以探讨其最佳手术时机。方法选择本院神经内科2010年10月~2013年4月接收的发病24 h内入院的126例急性脑出血患者为研究对象，采用随机数字法将所有患者均分为观察组和对照组，每组各63例。对照组患者采用常内科保守治疗，观察组在对照组的基础上行改良颅内血肿微创清除术；治疗3个月后，根据两组患者神经功能缺损程度评分（NDS）的下降情况比较两组患者的临床疗效；随访6个月后，比较观察组不同手术时机的患者再出血情况。结果治疗3个月后，观察组和对照组的总有效率分别为88.89%、38.10%，两组比较差异有统计学意义（P＜0.05）。随访6个月后，观察组6~24 h再出血率明显低于6 h以内和24~48 h，3个时间段再出血率比较差异有统计学意义（P＜0.05）。结论改良颅内血肿微创清除术治疗脑出血具有确切的临床效果，可显著提高患者的预后，值得在临床推广应用，且手术时机选择在脑出血后6~24 h为宜。
Objective To observe the clinical effects of improved and minimal invasive therapy in treatment of in-tracranial hematoma of patients with cerebral hemorrhage,in order to investigate the optimal timing of surgery. Methods 126 patients with acute cerebral hemorrhage treated in our hospital from October of 2010 to April of 2013 were chosen to be researched and they were randomly divided into two groups.Patients of control group were given conservative medical management, and patients of observation group were given improved and minimal invasive removal of intracra-nial hematoma on the basis of the control group.The clinical effect of two groups were compared according to the de-cline of neurological deficiency score （NDS）.After followed-up with 6 months,the rehaemorrhagia rate of observation group of different operation time were compared. Results After treatment with 3 months,the total effective rate of obser-vation group and the control group respectively was 88.89%,38.10%,the differences had statistically significant （P〈0.05）.After followed-up with 6 months,the rehaemorrhagia rate from 6 to 24 hours was lower than within 6 hours and from 24 to 48 hours,and the differences of three time buckets had statistically significant （P〈0.05）. Conclusion For pa-tients with cerebral hemorrhage,the clinical effect of improved and minimal invasive therapy is exact,and prognosis quality of patients are significantly increased,and worthy of popularization and application in clinic,and from 6 to 24 hours affter cerebral hemorrhage is the best operation time.
出处
《中国当代医药》
2014年第18期189-190,193,共3页
China Modern Medicine
关键词
脑出血
改良颅内血肿微创清除术
临床疗效
手术时机
Cerebral hemorrhage
Improved and minimally invasive removal of intracranial hematoma
Clinical effect
Operation timing
