摘要
目的:对比分析早产儿应用生长激素的临床效果。方法:随机将分娩的早产儿分为治疗组和对照组。对照组早产儿采取如吸氧、静脉输液、保温箱保温等不同的治疗方法;治疗组在对照组的基础上加用重组人生长激素。依据不同的目标方法检测指标变化,分析生长激素的临床疗效。结果:两组早产儿身高和身长比较,出生时的P>0.05(无统计学意义);治疗组纠正胎龄后3月、6月、12月的体重与对照组比较,P<0.05(差异有统计学意义);治疗组早产儿纠正胎龄后3月、6月、12月的身长与对照组比较,P<0.05(差异有统计学意义)。两组早产儿出生3天的血IGF-1水平,P>0.05(差异无统计学意义);治疗组纠正胎龄3个月和6个月的血IGF-1水平与对照组比较,P<0.05(差异有统计学意义)。治疗组在使用重组人生长激素后,血糖均值为(5.34±1.74)mmol/L,与对照组的(4.52±1.41)mmol/L相比较,P<0.05(差异有统计学意义)。治疗组早产儿血中胰岛素水平、生长激素释放多肽水平、葡萄糖/胰岛素比值与对照组比较,P<0.05(差异有统计学意义)。结论:早产儿应用生长激素的临床效果好,有利于患儿的生长发育,临床治疗中可以推广使用。
Objective：To compare the therapeutic effect of growth hormone in application of preterm Infants.Methods：Random delivery of premature infants were divided into treatment group and control group. The control group of premature infants to take such as oxygen, intravenous infusion, insulation insulation, different methods of treatment;the treatment group in the control group based on the use of recombinant human growth hormone. According to the change of different methods of target detection index, analysis of clinical efficacy of growth hormone.Results：Comparison of two groups of preterm birth height and length, P〉0.05 （not significant）;treatment group corrected age of March, June, December weight compared with control group, P〈0.05 （significant）; group of corrected age of March, June, December and the body height compared to the control group treatment, P〈0.05 （significant）. Two groups of preterm birth blood IGF-1 level on day 3, P〉0.05 （difference not significant）;group blood IGF-1 levels in treatment group corrected age of 3 months and 6 months and the control, P〈0.05 （significant）. The treatment group in the use of recombinant human growth hormone, and mean blood glucose was （5.34 ± 1.74） mmol/L, and the control group （4.52 ± 1.41） mmol/L, P〈0.05 （significant）. The treatment group of blood insulin level, growth hormone releasing peptide level, glucose/insulin ratio compared with the control group, P〈0.05 （significant）. Conclusion：The clinical effect of application of growth hormone, is conducive to children＇s growth and development, can be widely used in clinical treatment.
出处
《中国医药导刊》
2014年第5期860-861,863,共3页
Chinese Journal of Medicinal Guide
关键词
早产儿
生长激素
临床效果
Preterm children
Growth hormone
Clinical effects
