摘要
为了解我国临床淋病奈瑟菌对头孢曲松的耐药趋势,本研究利用中国期刊全文数据库检索公开发表的关于淋病奈瑟菌耐药性监测文献,按一定标准进行筛选、归类,计算和分析不同年份和地区淋病奈瑟菌对头孢曲松的耐药率与敏感率。共筛选文献101篇,数据主要集中在2000~2010年,经分析,全国耐药率：平均为0.66%,2008年最高为1.45%;全国敏感率：平均为68.83%,2001年最低仅56.44%。期间淋病奈瑟菌对头孢曲松的耐药率与敏感率在不同年份、不同地区均呈波动变化。从文献分析结果可知,2000~2010年虽然各地区耐药率有差异,但总体上我国临床分离淋病奈瑟菌对头孢曲松耐药率呈上升趋势,敏感率下降。
To investigate the situation and tendency of ceftriaxone （CRO） resistance to clinical isolations of Neisseria gonorrhoeae（Ng） , all the references related to drug resistance of Ng were retrieved through CNKI databank according to certain criteria. The resistance rates and sensibility of different types of bacteria were classified according to regions and years. A total of 101 documents were eventually amd nationally collected from 2000 to 2010. The average resistance rate of Ng to CRO was 0.66% and the highest one was 1.45% in 2008. The average sensibility was 68.83% and the lowest was 56.44% in 2001. In different regions and different years during this decade, the trends of Ng resistance to CRO were different and fluctuated. The analysis of references showed that the trend of Ng sensibility to CRO declined, although regional differences existed on the whole over the last decade.
出处
《药物流行病学杂志》
CAS
2014年第6期389-393,共5页
Chinese Journal of Pharmacoepidemiology
关键词
头孢曲松
淋病奈瑟菌
耐药率
Ceftriaxone
Neisseria gonorrhoeae
Resistance rate
