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胱抑素C在过敏性紫癜早期肾损伤中应用价值探讨 被引量:2

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摘要 目的探讨血清中胱抑素C(Cys C)对过敏性紫癜(HSP)患者早期肾损害的临床诊断中的价值。方法采用颗粒增强透射免疫比浊法检测29例HSP患者(观察组)和20例健康体检儿童(对照组)血清Cys C,同时收集临床指标24h尿蛋白(UTP/24h)和血清肌酐(Scr)。结果 HSP患儿血清Cys C水平[(2.00±0.54)mg/L]高于健康对照组[(0.84±0.30)mg/L],且患者中血清Cys C随着尿蛋白水平的升高而升高,各组之间比较,差异均有统计学意义(P<0.05)。对照组、A组及B组之间血肌酐水平两两比较,差异无统计学意义(P>0.05);C组血肌酐水平与其他各组比较,差异有统计学意义(P<0.05)。血清Cys C水平与Scr水平呈正相关(r=0.63,P<0.01)。结论血清Cys C的测定对HSP早期肾损伤的诊断具有良好的临床价值。
出处 《重庆医学》 CAS CSCD 北大核心 2014年第17期2211-2213,共3页 Chongqing medicine
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