摘要
目的：评价中药联合肝动脉导管化疗栓塞（TACE）后序贯射频消融（RFA）治疗大肝癌的疗效。方法72例（95个病灶）大肝癌患者（肿瘤直径5.1-14.5 cm），TACE 治疗后1周行 RFA治疗，24 h CT 评价，如有漏空现象，给予 RFA 1-2次补充治疗，最后一次 RFA 治疗后1个月再次行TACE 巩固治疗。术后所有患者均服用中药健脾化痰方。随访观察治疗效果、并发症和患者生存时间。结果 RFA 后完全缓解36例，部分缓解22例，病变进展14例。并发症7例（9.72%），包括电极片灼伤皮肤2例，气胸3例，腹腔出血2例。大肝癌 TACE 序贯 RFA 治疗后6个月、1、2、3年生存率分别为97.2%（70例）、73.6%（53例）、47.2%（34例）、33.3%（24例）。结论中药联合 TACE 后序贯RFA 是治疗大肝癌的一种有效治疗模式。
Objective To evaluate the efficacy on large hepatocellular carcinoma（HCC）treated with Chinese medicines combined with radiofrequency ablation（RFA）after transcatheter arterial chemoemboliza-tion（TACE）. Methods Seventy - two cases of large HHC had 95 foci（5. 1 - 14. 5 cm in diameter）. RFA was applied after TACE. CT assessment was given in 24 h. RFA for one or twice were supplemented if leaka-ges were discovered. TACE was consolidated after the last RFA in one month. Results Thirty - six cases were completed ablated after RFA,22 cases basically ablated and 14 cases partially ablated. Seven cases （9. 72% ）presented complications,including 2 cases of skin burns,3 cases of pneumothorax and 2 cases of abdominal hemorrhage. The survival rates were 97. 2%（70 cases）,73. 6%（53 cases）,47. 2%（34 cases）and 33. 3%（24 cases）in 6 months,1,2 and 3 years after RFA after TACE separately. Conclusion Chinese medi-cines combined with RFA after TACE is the effective therapeutic program for the treatment of large HCC.
出处
《世界中西医结合杂志》
2014年第6期634-637,共4页
World Journal of Integrated Traditional and Western Medicine
关键词
大肝癌
射频消融
肝动脉导管化疗栓塞
Large Hepatocellular Carcinoma
Radiofrequency Ablation
Transcatheter Arterial Che-moembolization
