摘要
目的 :研究微波辐照对小鼠肾皮质和睾丸中脂质过氧化产物丙二醛 (MDA)含量和超氧化物歧化酶 (SOD)活性的影响。方法 :选用频率 2 4 50MHz、功率密度 10mW /cm2 的微波照射小鼠 ,用TBA比色法和NBT羟胺法 ,检测组织中MDA含量和SOD活性。结果 :微波辐照后 1,6 ,12 ,2 4d ,小鼠的肾皮质和睾丸中MDA含量均升高 ,2 4d达到最高量 (P <0 .0 1) ;SOD活性均降低 ,2 4d降到最低点 (P <0 .0 1)。结论 :该辐照条件下 ,微波辐照可致肾皮质和睾丸中自由基产量过多 ,SOD活性降低。
Objective: To observe the effects of microwave on the activity of SOD and the contents of MDA in renal cortex and testis of mice. Methods: Microwave generator(2 450 MHz, 10 mW/cm 2) was used to expose mice; NBT,DTNB and TBA were used to mearure the activity of SOD and the contents of MDA in renal cortex and testis of the mice after microwave exposure.Results: The content of MDA in renal cortex and testis of the mice increased progressively on days 1,6,12 and reached the highest level on day 24 after the microwave exposure (P<0.01). The activity of SOD in renal cortex and testis of the mice decreased progressively on days 1, 6, 12 and reached the lowest level on day 24 after the microwave exposure (P<0.01). Conclusions: Microwave exposure can produce reactive oxygen free radicals and lead to depress SOD activity. [
出处
《军事医学科学院院刊》
CSCD
北大核心
2001年第1期24-26,共3页
Bulletin of the Academy of Military Medical Sciences
