摘要
目的 分析合肥市Mtb与HIV感染者或AIDS患者的双向筛查情况，为今后的双重感染防治工作提供科学依据。 方法 在2011—2013年合肥市所辖县（市、区）能随访到的1422例HIV感染者或AIDS患者中筛查结核病，动员新登记的5772例结核病患者进行HIV抗体检测。应用SPSS 21.0软件进行数据处理，采用趋势性χ^2检验和列联表χ^2检验，P〈0.05为差异有统计学意义。 结果 2011—2013年HIV感染者或AIDS患者接受结核病检查率分别为92.62%（276/298）、99.57%（458/460）和98.29%（688/700），3年间HIV感染者或AIDS患者接受结核病检查率呈显著上升趋势（χ趋势^2=18.57, P〈0.001）；2011—2013年登记的结核病患者接受HIV抗体检测率分别为40.17%（1701/4234）、38.20%（1632/4272）和53.49%（2439/4560），3年间结核病患者接受HIV抗体检测率呈显著上升趋势（χ趋势^2=162.83, P〈0.001）；实行“三位一体”结核病防治模式地区的结核病患者接受HIV抗体检测率为60.99%（2029/3327），显著高于未实行“三位一体”地区的结核病患者接受HIV抗体的检测率［33.25%（410/1233）］（χ^2=1083.62，P〈0.001）。 结论 Mtb与HIV感染双向筛查是发现Mtb与HIV双重感染患者最主要的途径，因此，积极开展并做好双向筛查工作对于提高双重感染者的发现率、有效控制Mtb与HIV双重感染疫情、改善双重感染患者生活质量及降低死亡率具有重要意义。
Objective To describe the status of the bi-directional screening model for Mycobacterium tuberculosis（Mtb） and human immunodeficiency virus（HIV）/AIDS infection in Hefei city, and to provide the scientific evidence for prevention and control of tuberculosis（TB） and HIV co-infection. Methods One thousand four hundred and twenty-two HIV/AIDS patients were screened for Mtb in 2011—2013 in Hefei, and 5772 newly registered TB patients were screened for the HIV antibody. All statistical analyses were performed using SPSS 21.0 statistical software, and Chi-square test was used for categorical variables, 0.05 was set as the criteria of statistical significance. Results During 2011—2013, the TB screening rates among HIV/AIDS patients were 92.62%（276/298）, 99.57%（458/460） and 98.29%（688/700） respectively, with significant increasing trend （χtrend^2=18.57, P〈0.001）. During 2011—2013, the HIV screening rate of registered TB patients were 40.17%（1701/4234）, 38.20%（1632/4272） and 53.49%（2439/4560） respectively, which showed the significant increasing trend as well （χtrend^2=162.83, P〈0.001）. The HIV antibody screening rate in new TB control network areas was 60.99%（2029/3327）, which was significantly higher than other areas（33.25%,410/1233）（χ^2=1083.62, P〈0.001）. Conclusion The bi-directional screening for Mtb and HIV is the main route to detect Mtb/HIV co-infection patients, accordingly,actively carrying out the screening work has important implications for improving the detection rate of co-infection, effective control of Mtb/HIV co-infection, improving the quality of life and mortality of co-infected patients.
出处
《中国防痨杂志》
CAS
2014年第7期552-555,共4页
Chinese Journal of Antituberculosis
关键词
结核
获得性免疫缺陷综合征
重叠感染
普查
合肥市
Tuberculosis
Acquired immunodeficiency syndrome
Superinfection
Mass screening
Hefei city
