摘要
目的：探讨超早期溶栓治疗脑梗塞疗效及早期和远期疗效差异的可能机制。方法：５４例患者被分为二组，溶栓治疗组和对照组。在治疗前、治疗后 ２４小时、３月分别进行 ＥＳＳ、Ｂａｒｔｈｅｌ指数和 Ｒａｎｋｉｎ评分，比较前后效果。结果：溶栓治疗组对照组在２４小时ＥＳＳ评分无显著异性（Ｐ＞０．０５）但３月后溶栓治疗组疗效明显优对照组（Ｐ＜０．０５＝。结论：超早溶栓治疗脑梗塞的远期效比早疗效好，其差异的可能是缺血性神经元顿抑（ｉｓｃｈｅｍｉｃ ｎｅｕｒｏｎ ｓｔｕｎｎｉｎｇ）。
Objective: It is attempted to study the mechanisms of the differences between the earlyu clincal outcome and long - term clinical outcom of the thrombolytic therapy for hyperacute ischemic stroke. Methods: Hopitalaized 54 cases patients ere divided into the control groupand the thromboytic therapy group ESS.Barthel index and Rankin scale was used for the assessment of the outcome for the patients before the treatment， 24 hrs and 3 months after the treatement in order to compare the therapeutic results. Results: It was found that there was no significant difference in the efficacy 24 hrs after the treatment between the therapeutic group and the control group ( P＞0. 05). But the findings showed that encouraging efficacy was achieved in based on assessment for the patients 3 months after the treatment in the thrombolytic group( P＜ 0. 05＝. Conclusion: It as suggested that the long-term outcome has been observed better than the early outcome in the patients treated with the hyperacute thrombolytic therapy. The considerable difference between early clinical outcome and long-term clinical outcome may be due to the effect of the possible ischmeic neuron stunning.
出处
《脑与神经疾病杂志》
2001年第2期71-73,共3页
Journal of Brain and Nervous Diseases
关键词
缺血性脑梗塞
溶栓治疗
预后
顿抑
cerebral infarction throbllytic therapy prognosis stunning
