摘要
本文以丹参为对照观察菊花水提液对大鼠心、脑组织体外孵育时自发脂质过氧化(LPO)反应的影响;对羟自由基(·OH)引发的小鼠心、脑匀浆和心、脑线粒体膜LPO反应的影响。结果表明:菊花水提液对上述过程的抑制作用与丹参相当;小鼠连续灌胃菊花水提液2g·kg^(-1)·d^(-1)、4g·kg^(-1)·d^(-1)15d,其心、脑组织LPO反应产物丙二醛含量均显著低于生理盐水组。上述结果表明菊花水提液具有抑制自由基生成及抑制自由基引发的LPO反应的作用。
This paper reported the effect of water extract of Flos Chrysanthemi on lipid per-oxidation (LPO)of heart and cerebral ho-mogenate from rats incubated in 37 ?0.5℃, of heart and cerebral homogenate from mice induced by OH, of heart and cerebral mitochondria member induced by OH, which was compared with Radix Salviae Miltiorrhizae. The results showed that the inhibition effect of water extract of Flos Chrysanthemi on above - mentioned LPO was equal to Radix Salviae Miltiorrhizae. It was concluded that water extract of Flos Chrysanthemi could restrain the produce of free radicals and LPO induced by free radicals.
出处
《中药材》
CAS
CSCD
北大核心
2001年第2期122-124,共3页
Journal of Chinese Medicinal Materials
基金
浙江省中医药局资助课题
