摘要
目的 探讨急性一氧化碳中毒后迟发性脑病 (DEACMP)患者脑脊液 (CSF)免疫球蛋白 (Ig)和肿瘤坏死因子 - α(TNF- α)的变化。方法 采用单向琼脂扩散法和双抗体夹心 EL ISA法测定 39例 DEACMP患者入院时、出院前 Ig G、Ig A、Ig M、TNF- α的含量 ,并与 30例对照组作比较。结果 患者组入院时 CSF Ig G、Ig A含量明显增高 ,Ig M、TNF- α含量正常 ,但入院时、出院前比较无显著差异。
Objective To explore the change of CSF Igs and TNF α in patients with delayed encephalopathy after acute carbon monoxide poisoning (DEACMP). Methods There were 39 patients with DEACMP and 30 controls in this study. Among the patients,the level of Igs and TNF α were detected by simple agar diffusion and ELISA at early stage of hospitalization and pre discharged,respectively. Results CSF IgG and IgA in patients were significantly higher than those in controls(P<0.05). There was no significant difference in IgM,TNF α between the two groups(P>0.05). No significant difference in IgG,IgA,IgM,TNF α were found when compared them between the two point of early stage of hospitalization and pre discharged. Conclusion The onset of DEACMP maybe associated with immunity dysfunction.
出处
《中风与神经疾病杂志》
CAS
CSCD
北大核心
2001年第3期173-174,共2页
Journal of Apoplexy and Nervous Diseases
