摘要
目的 :观察高原低氧环境下人体红细胞增多和血液粘度间的关系。方法 :对进入高原不同时间人群进行血液流变学 (红细胞压积、血液粘度、红细胞变形性和聚集性以及供氧指数等 )检测和分析。结果 :①红细胞压积和红细胞变形性随进住高原时间的延长而显著升高 ;②血液粘度在进住高原的早期明显升高 ,后期恢复正常 ;③红细胞的聚集性在进住高原的早期显著升高 ,后期则下降 ;④组织供氧指数在进住高原的早期明显降低 ,而后期恢复正常。结论 :在高原低氧环境下 ,人体血液粘度不随红细胞压积增高按比例升高 ,红细胞变形性增强和红细胞聚集性下降可能抑制了红细胞压积增高所引起的血液粘度的过度升高 。
Aim:To investigate the relationship of high hematocrit with changes of the blood viscosity during in the environment of altitude hypoxia. Methods: Index of hemorheo1ogy was determined from populations with different time of inhabit highland and normal controls.Results: ① Hematocrit and RBC deformability were higher in all highland populations than that in normal controls,these increase were time dependent. ②The blood viscosity was increased significantly during the early stage of inhabit highland,and restored normal in late stage. ③RBC aggregability was reduced significantly with time dependent in highland populations. ④The oxygen content of tissue was reduced significantly during the early stage of inhabit highland,and restored normal in late stage. Conclusions: In the environment of altitude hypoxia,RBC deformability increase and RBC aggregability decrease can suppress blood viscosity increase induced by erythrocyhemia,these compensatory regulation is help to maintain the normal oxygen content of tissue.
出处
《中国应用生理学杂志》
CAS
CSCD
北大核心
2001年第3期231-235,共5页
Chinese Journal of Applied Physiology
