摘要
目的 :研究蛰虫抗肝纤维化的作用。方法 :以腹腔注射猪血清制备大鼠肝纤维化模型 ,以ALT、GGT、TP、Alb、A /G比值、IV .C、LN、HA及肝脏组织病理变化为指标 ,观察蛰虫对大鼠肝纤维化的影响。结果 :蛰虫能提高肝纤维化大鼠TP、ALb含量及A/G比值 ,有降低ALT、GGT、IV .C、LN、HA的作用 ,并能改善肝脏组织病理学变化。结论 :蛰虫有保护肝细胞、减轻肝细胞变性坏死 ,恢复肝细胞结构和功能 ;减少纤维组织增生 ,阻止纤维化发展 。
Objective:To study the effects of eupolyphaga seu steleophaga on hepatic fibrosis.Methods:The rat immunohepatic fibrosis model was made by intraperitoneal injection of porcine serum and treated with eupolyphaga seu steleophaga.The ALT?GGT?TP?ALb?A/G?IV.C?LN?HA and the pathological change of the liver were observed,Results:Eupolyphaga seu steleophaga could increase TP?ALb?A/G,decrease ALT?GGT?IV.C?LN?HA and improve the pathological change.Conclusions:Eupolyphaga seu steleophaga could protect hepatic cells,alleviate degeneration and necrosis,recover structure and function,and reduce the proliferation of fibrous tissue.
出处
《中医药研究》
2001年第4期38-40,共3页
Research of Traditional Chinese Medicine
