摘要
目的 :研究银杏叶提取物对老年糖耐量减退患者血清胰岛素及血脂、血糖水平的影响 ,探讨银杏叶提取物对胰岛素抵抗的改善作用及机制。方法 :对 6 8例老年糖耐量减退患者应用银杏叶提取物金钠多静脉滴注 2 8d ,每日一次 ,治疗前后分别测定脂蛋白及 75 g葡萄糖耐量试验 (OGTT)各点的胰岛素、血糖的血清浓度。 结果 :6 8例经治疗后TG、VLDL及 0 ,6 0 ,12 0min各点的血糖及胰岛素水平均显著降低 (P <0 0 5 ) ,多元回归分析 ,TG、VLDL与OGTT各点的血糖及胰岛素水平明显相关。结论 :银杏叶提取物可通过调节血脂水平 ,尤其是TG、VLDL水平 ,改善老年糖耐量减退患者的血糖代谢及高胰岛素血症 。
Objective:By studying the effect of ginkgo leaf extract on insulin,blood-lipid and glucos levels in the aged patients with impaired glucose tolerance,to explore the improvement and mechanism on insulin resistance of ginkgo leaf extract.Method:68 aged IGT patients were treated with ginkgo leaf extract-Ginaton once daily for 28 days,the concentrations of blood lipid and insulin,glucose in OGTT every point were determined both before and after receivin.Results:After treatment,the level of TG,VLDL,BS and insulin of 0,60,120 min were belowed significantly (P<0 05),multivariate regression analysis revealed a significantly correlation between TG,VLDL and glucose,insulin OGTT every point.Conclusion:By regutating blood-lipid,ginkgo leaf exeract can improve glucose metabolism and hyperinsulinemia in aged IGT patient,and thus can improve insulin resistance.\;
出处
《安徽医学》
2001年第5期5-7,共3页
Anhui Medical Journal
