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糖尿病视网膜病变细胞外间质和粘附分子的研究进展 被引量:3

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摘要 细胞外间质 (ECM)、粘附分子 (AMs)及生长因子 (GFs)与糖尿病微血管病变有密切的关系。研究不同阶段糖尿病视网膜病变在基膜、细胞表面等部位ECM、AMs的异常改变有助于了解其发病机制。ECM、AMs成分的改变和交联异常与非酶糖基化导致的糖基化终末产物有关 ,而许多GFs能诱导和促进此过程的发生和发展。血液ECM成分和AMs的含量测定对于糖尿病微血管病变的早期诊断、病情监测、疗效观察和预后判断都不失为良好的指标。
出处 《国外医学(内分泌学分册)》 2001年第5期250-252,共3页 Foreign Medical Sciences(Section of Endocrinology)
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