渗透性开放血脑屏障的原理机制和治疗应用
被引量:4
摘要
血脑屏障渗透性开放是通过血管扩张和脑血管内皮细胞的皱缩而介导的 。
出处
《国外医学(神经病学.神经外科学分册)》
2001年第4期253-256,共4页
Foreign Medical Sciences(Section On Neurology & Neurosurgery)
参考文献17
-
1Rapoport SI, Hori M, Klatzo I. Testing of a hypothesis for osmotic opening of the blood - brain barrier. Am J Physiol, 1972, 223(2): 323- 331
-
2Rapoport SI. Microinfarction: Osmotic BBB opening of microcrystals in infusate? J Neurosurg, 1991, 74(4): 685
-
3Remsen LG, Pagel MA, McCormick CI, et al. The influence of anesthetic choice, PaCO2, and other factors on osmotic blood - brain barrier disruption in rats with brain tumor xenografts. Anesth Analg, 1999, 88 (3): 559-567
-
4Lin W, Paczymski RP, Kuppusamy K, et al. Quantitative measurements of regional cerebral blood volume using MRI in rats: effects of arterial carbon dioxide tension and mannitol. Magn Reson Med, 1997, 38 (3): 420-428
-
5Muldoon LL, Nilaver G, Kroll RA, et al. Comparison of intracerebral inoculation and osmotic blood - brain barrier disruption for delivery of adenovirus, herpesvirus, and iron oxide particles to normal rat brain.Am J Pathol, 1995, 147(6): 1840- 1851
-
6Siegal T, Rubinstein R, Bokstein F, et al. In vivo assessment of the window of barrier opening after osmotic blood - brain barrier disruption in humans. J Neurosurg, 2000, 92(4): 599 - 605
-
7Barth RF, Yang W, Rotaru JH, et al. Boron neutron capture therapy of brain tumors: Enhanced survival following intracarotid injection of either sodium borocaptate or boronophenylalanine with or without blood - brain barrier diruption. Cancer Res, 1997, 57(6): 1129-1136
-
8Sato S, Kawase T, Harada S, et al. Effect of hyperosmotic solutions on human brain tumour vasculature. Acta Neurochir (Wien), 1998, 140 (11): 1135- 1141
-
9Dahlborg SA, Henner WD, Crossen JR, et al. Non - ADS primary CNS lymphoma: The first example of a durable response in a primary brain tumor using enhanced ehemotherapy delivery withont cognitive loss and withont radiotherapy. Cancer J Sci Am, 1996, 2(3): 166- 174
-
10Oshimoto T, Siesjo BK. Posttreatment with the immunosuppressant cyclosporin. A in transient focal ischemia. Brain Res, 1999, 839(2):283 - 291
同被引文献51
-
1王明盛,杨正明,陈坚.卡铂、威猛、甲氨蝶呤、尼莫地平联用对脑胶质瘤的抑制作用[J].山东医药,2005,45(10):22-23. 被引量:5
-
2章龙珍,曹远东,陈勇,于常州,庄明.全脑常规分割外照射对大鼠血脑屏障药物通透性的影响[J].中华放射肿瘤学杂志,2006,15(3):229-232. 被引量:17
-
3Regina A, Demeule M, Laplante A, et al. Muhidrug resistance in brain tumors: roles of the blood-brain barrier. Cancer Metastasis Rev, 2001,20(1-2) : 13-25.
-
4Fortin D, Salame JA, Desjardins A, et al. Technical modification in the intracarotid chemotherapy and osmotic blood-brain barrier disruption procedure to prevent the relapse of carboplatin-induced orbital pseudotumor. Am J Neuroradiol, 2004,25 : 830-834.
-
5McDannold N, Vykhodtseva N, Hynynen K. Targeted disruption of the blood-brain barrier with focused ultrasound: association with cavitation activity. Phys Med Biol, 2006,51(4): 793-807.
-
6Sabel M, Rommel M, Kondakci F, et al. Locoregional opening of the rodent blood-brain barrier for paclitaxel using Nd:YAG laser-induced thermo therapy: a new concept of adjuvant glioma therapy? Lasers Surg Med,2003, 33(2): 75-80.
-
7van Vulpen M, Kal HB, Taphoom M J, et al. Changes in blood-brain barrier permeability induced by radiotherapy: implications for timing of chemotherapy? Oncol Rep,2002, 9(4): 683-688.
-
8Qin D, Ou G, Mo H, et al. Improved efficacy of chemotherapy for glioblastoma by radiation-induced opening of blood-brain barrier: clinical results. Int J Radiat Oncol Biol Phys, 2001,51 (4) : 959- 962.
-
9Qin D, Ma J, Xiao J, et al. Effect of brain irradiation on blood-CSF barrier permeability of chemotherapeutic agents. Am J Clin Oncol, 1997,20(3) : 263-265.
-
10顾科,张军宁.成人Ⅱ级以上脑胶质瘤术后同步放化疗疗效分析[J].肿瘤防治研究,2007,34(8):626-628. 被引量:13
引证文献4
-
1曹远东,章龙珍,陈勇,董红燕,于红丽,于常州.全脑常规照射对血脑屏障功能影响的实验研究[J].中华放射医学与防护杂志,2008,28(3):245-249.
-
2曹远东,章龙珍,陈勇,董红燕,于红丽,庄明.^(60)Co-γ射线全脑常规照射后大鼠血脑屏障的电镜观察[J].东南大学学报(医学版),2008,27(5):344-348. 被引量:2
-
3赵亚群,李素雅,王永,狄淬砺,汤可,周敬安.安宫牛黄方剂与甘露醇促进十一氢巯基十二硼化钠透过血脑屏障的研究[J].中华临床医师杂志(电子版),2012,6(10):174-175. 被引量:4
-
4李亮亮,王建祯.脑胶质瘤超选择动脉化疗的研究进展[J].山东医药,2014,54(2):103-105. 被引量:4
二级引证文献10
-
1汤婷,吴琪,王汉东,韩艳玲,纪祥军.经动脉介入化疗治疗胶质瘤疗效及安全性Meta分析[J].临床军医杂志,2022,50(2):160-164.
-
2程宏文.非小细胞肺癌脑转移同步放化疗疗效分析[J].临床肺科杂志,2010,15(3):348-349. 被引量:4
-
3张雷,陈隆益,何永生,谭海斌,徐玉川,董丹丹,杨果,刘卫东,黄光富.放射外科治疗脑星形胶质细胞瘤的病理改变对比研究[J].中华神经医学杂志,2011,10(9):905-909. 被引量:5
-
4刘艳,杨林.化疗联合放疗与单纯放疗治疗胶质瘤的疗效分析[J].安徽医学,2016,37(3):295-298. 被引量:5
-
5陆建勋.中枢神经系统神经上皮细胞肿瘤的流行病学研究[J].中国实用神经疾病杂志,2015,18(11):48-50. 被引量:2
-
6胡华白,马俊杰.安宫牛黄丸治疗急性脑血管病临床及药理机制研究进展[J].世界科学技术-中医药现代化,2015,17(7):1510-1513. 被引量:19
-
7周至品,唐秀能,叶晓雪.临床药师参与1例难治性颅内感染患者的治疗实践[J].中国药师,2016,19(5):955-957. 被引量:1
-
8田超,袁梦晨,王晓峰,吴爱明,孙逸坤,高永红.醒脑开窍药治疗中风病实验研究进展[J].中西医结合心脑血管病杂志,2018,16(15):2158-2161. 被引量:14
-
9张勇军,沙城华,王军.安宫牛黄丸辅助西医治疗急性脑出血痰热内闭清窍证患者疗效及对氧化应激指标的影响[J].现代中西医结合杂志,2019,28(28):3101-3104. 被引量:23
-
10张婷,温妮妮,刘又溶,王娇,赵春娟.颅脑肿瘤患者化疗后并发症观察及护理[J].山西医药杂志,2020,49(20):2854-2856. 被引量:2
-
1姚静,周建平,卢韵,于力,平其能.聚氧乙烯蓖麻油微乳对血脑屏障通透性的影响[J].中国药科大学学报,2005,36(1):27-30. 被引量:20
-
2秦鑫,张英起,颜真.跨越血脑屏障[J].生命的化学,2003,23(3):222-224. 被引量:6
-
3王来海,王长虹,郭田荣,徐华.奥氮平治疗精神分裂症的临床疗效及安全性[J].中国临床药学杂志,2002,11(5):287-288. 被引量:3
-
4毛小平,龚梅芳,钟萍.山莨菪碱对脑血管内皮细胞与自由基的影响[J].微循环学杂志,1996,6(4):15-16. 被引量:9
-
5袁波,夏志民,杨明,谭占国,王景顺.甘露醇渗透性开放血脑屏障的时间窗对脑脊液中药物浓度的影响[J].中国医学创新,2009,6(32):1-2. 被引量:3
-
6周长征.自微乳化药物传递系统的研究进展[J].内蒙古中医药,2012,31(10):122-122. 被引量:3
-
7刘娜,高祥春.冰片可控性开放血脑屏障的实验研究[J].潍坊医学院学报,2007,29(5):398-400. 被引量:6
-
8周利婷,陶娌娜,曲晓宇,张四喜,宋燕青.两种丹酚酸注射剂在小鼠体内组织分布的研究[J].中国医院药学杂志,2017,37(4):356-359. 被引量:6
-
9刘晓.甘露醇开放血脑屏障在小细胞肺癌治疗中的应用探讨[J].海峡药学,2016,28(8):134-135. 被引量:3
-
10郑慧军,常金生,常枫,王文革,石小斌,魏大年.静脉输注甘露醇开放血脑屏障对抗生素透过血脑屏障的影响[J].中华实验外科杂志,2004,21(4):475-477. 被引量:5