摘要
对181例女性胆囊结石病人的血清总胆固醇(T-ch)、甘油三脂(TG)、β-磷脂(β-LP)、高密度脂蛋白胆固醇(HDL-ch)、高密度脂蛋白胆固亚类Ⅱ(HDL_2-Ch)、高密度脂蛋白胆固醇亚类Ⅲ(HDL_3-ch)、低密度脂蛋白胆固醇加极低密度脂蛋白胆固醇(LDL-ch+VLDL-ch)等19个变量进行了单因素及多因素分析。分析结果表明,单因素分析19个变量中12个变量两组有显著差异;趋势检验发现T-ch,β-LP及LDL-ch+VLDL-ch与女性胆囊结石的发生有明显的剂量—效应关系。多因素条件Logistic回归分析结果显示T-ch,TG,β-LP,LDL-ch+VLDL-ch及HDL_2-ch为致病的危险因素。另外还提示该病的发生与饮食、冠心病史和胆石症家族史有关。
A case-control study of the relation between serum lipids and related factorsin 181 female cholelithiasis patients was carried out. 19 variables were analyzedby means of single and multiple factors analyses. They included serum total choleste-rol (T-ch), serum triglyceride (TG), β-phospholipid (β-LP), high-density-lipoprotein cholesterol (HDL-ch), substraction Ⅱ of serum high-density-lipoproteincholesterol (HDL_2-ch), substraction Ⅲ of high-density-lipoprotein cholesterol(HDL_3 ch), low-density-lipoprotein cholesterol plus very-low-density-lipoproteincholesterol (LDL-ch+VLDL-ch). 12 of the variables were considered as susplciousrisk factors. Trend tests showed that a quantity-efficacy relation existed betweencholelithrasis in women and T-ch, β-LP, and LDL-ch+VLDL-ch. Conditionalmultiple logistic regression analysis of above 12 factors showed that 8 factors ofthem might be the risk factors associated with the discase. They are T-ch, β-LP,LDL-ch+VLDL-ch, TG, HDL_2-ch, a fat-rich diet, a history of cororary diseaseand a family history of gallstone disease.
出处
《青岛医学院学报》
1991年第3期177-181,共5页
Acta Academiae Medicinae Qingdao Universitatis
关键词
胆结石
女性
高血脂病
cholelithiasis
female
hyperlipidemia
conditional logistic regression analysis
epidemiolologic method
