期刊文献+

以端粒酶为靶点的天然抗癌药物筛选策略 被引量:3

Screen for natural products as Inhibitor of Telomerase in anti-tumor activity
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摘要 0 引言肿瘤是一系列基因异常累加的遗传性疾病.人类癌基因的激活是由于基因数量的增加或结构的变化所致[1].随着人类基因组草图的初步完成,接下来的工作重点必然是找出疾病相关基因及利用这些基因提供治疗疾病的新手段.
出处 《世界华人消化杂志》 CAS 2001年第12期1360-1363,共4页 World Chinese Journal of Digestology
基金 国家博士后基金 国家自然科学基金 No.29972017
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  • 1ZHAN Wen Hua, MA Jin Ping, PENG Jun Sheng, GAO Jing Song, CAI Shi Rong, WANG Jian Ping, ZHENG Zhang Qing and WANG Lei.Telomerase activity in gastric cancer and its clinical implications[J].World Journal of Gastroenterology,1999,5(4):44-47. 被引量:25
  • 2李宜明,沈业寿,王清,季俊虬.抗肿瘤药物的筛选方法[J].安徽大学学报(自然科学版),2005,29(1):90-96. 被引量:6
  • 3Suash Sharma,Mehar C. Sharma,Maribeth H. Johnson,Mimi Lou,Alok Thakar,Chitra Sarkar.Esthesioneuroblastoma — a clinicopathologic study and role of DNA topoisomerase alpha[J]. Pathology & Oncology Research . 2007 (2)
  • 4Pacheco FJ,Serbin J,Dang Det al.Involvement of lyso-somalcathep sins in the cleavage of DNA topoisomerase Iduring necrotic cell death. A rthritis Rheum . 2005
  • 5Xiao H,Mao Y,Desai SDet al.The topoisomeraseⅡbetacircular clamp arrests transcription and signals a 26S protea-some pathway. Proceedings of the National Academy of Sciences of the United States of America . 2003
  • 6Kunnumakkara AB,Anand P,Aggarwal BBet al.Curcu-min inhibits proliferation,invasion,angiogenesis and me-tastasis of different cancers through interaction with multi-ple cell signaling proteins. Cancer Letters . 2008
  • 7Zhou QJ,Li L,Xiang JFet al.Screening potential anti-tumor agents from natural plant extracts by G-quadruplexrecognition and NMR methods. Angewandte Chemie International Edition . 2008
  • 8Brusselmans K,De Schrijver E,Heyns W.Epigallocatechin-3-gallate is a potent natural inhibitor of fatty acid synthase in intact cells and selectively induces apoptosis in prostate cancer cells. International Journal of Cancer . 2003
  • 9Athar M,Back JH,Kopelovich L,et al.Multiple molecular targets of Resve-ratrol:anti-carcinogenic mechanisms. Archive of Biochemistry and Biophysics . 2009
  • 10Khan N,Afaq F,Saleem M,et al.Targeting multiple signaling pathways by green tea polyphenol(-)-epigallocatechin-3-gallate. Cancer Research . 2006

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