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应用组织追踪法评价左室功能的研究 被引量:58

Tissue tracking allows rapid and accurate evaluation of left ventricular function
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摘要 目的 用超声心动图组织追踪法评价左室功能。方法 对 90例具有不同左室收缩功能患者的心尖四腔心、心尖长轴和心尖二腔心切面 ,用组织追踪法和M型超声心动图法记录收缩期二尖瓣瓣环向心尖方向的运动位移。所有患者均用Simpson方法确定左室射血分数 ,其中 2 7例患者又做了左室造影。 结果 在 5 0例患者中 (包括 2 5例正常左室功能患者和 2 5例左室整体功能减退患者 ) ,组织追踪法从二尖瓣环的 6个位置测得的收缩期平均二尖瓣瓣环距离与M型测得的值非常接近 (r =0 .99,P <0 .0 0 1) ,与左室射血分数的相关性很匹配 (r =0 .97,P <0 .0 0 1)。用组织追踪法测定的收缩期二尖瓣瓣环下移距离 4.8mm作为一个切断点的值(cut ofvalue) ,预测左室射血分数≤ 30 %的敏感性为 98%,特异性为 78%。但在陈旧性心肌梗死患者中 ,组织追踪法从二尖瓣瓣环的 6个位置测得的收缩期平均二尖瓣瓣环下移的距离与左室射血分数的相关性是较低的 (r= 0 .87,P <0 .0 0 1)。结论 组织追踪法测收缩期二尖瓣瓣环下移距离可为临床提供一种简单快速和无创伤性评价左室功能的方法。 Objective To assess the ability of tissue tracking for assessment of left ventricular(LV) function by determination of the systolic mitral annular displacement (MAD).Methods Ninety patients with different LV function were studied,including 25 subjects with normal LV function,25 patients with homogenous depression of LV function due to cardiomyopathy and 40 patients with prior myocardial infarction(MI) and regional depression of myocardial contractlity.The systolic MAD was determined by tissue tracking and M-mode echocardiography.The apical four chamber,long axis and two chamber views were used to determine the MAD of 6 sites.LV ejection fraction (LVEF) was determined by 2D echocardiography using Simposon′s rule in all patients and contrast cineangiography in 27 patients.Results Tissue tracking was possible in all patients.In 50 patients,including 25 patients with normal LV function and 25 patients with homogenous depression of LV function,mean MAD measured from 6 sites of the mitral annulus correlated closely with MAD determined by M-mode (r= 0.99,P< 0.001) and with the LVEF determined by 2D echocardiography (r= 0.97,P< 0.001).Using a cut-off value of 4.8 mm for the MAD determined by tissue tracking,LVEF≤30% can be predicted with a sensitivity of 98% and a specificity of 78%.In patients with prior MI correlation between the mean MAD measured by tissue tracking and the LVEF determined by 2D echocardiography was lower(r= 0.87,P< 0.001).Conclusions Systolic MAD determined by tissue tracking correlates closely with MAD determined by M-mode and with LVEF determined by 2D echocardiography.Thus,MAD determined by tissue tracking provides a simple,rapid,and noninvasive tool to assess global LV function.
出处 《中华超声影像学杂志》 CSCD 2001年第12期715-718,共4页 Chinese Journal of Ultrasonography
关键词 超声心动描记术 左心室功能 心肌疾病 心肌梗塞 Echocardiography Ventricular function,left Myocardial diseases Myocardial infarction
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参考文献10

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