摘要
目的:探讨头孢吡污与头孢他啶治疗细菌性感染所产生的经济效果。方法:根据文献选择细菌性感染的病人129例,随机分成头孢吡肟(A)组65例和头孢他啶(B)组64例分别给与治疗,运用药物经济学的成本—效果分析方法进行分析评价。结果:A 组和 B 组有效率分别为92.3%及90.6%,痊愈率各为72.3%及68.8%。A 组的成本—效果比在下呼吸道感染、尿路感染、腹腔和胆道感染、败血症方面均低于 B 组。结论:头孢吡肟在治疗敏感菌所致的下呼吸道感染、尿路感染、腹腔和胆道感染、败血症方面优于头孢他啶,是一种成本—效果较好的药物。
Objective:To evaluate the cost-efficacy of cefepime and ceftazidime in the treat- ment of bacterial infections.Methods:One hundred and twenty nine patients with bacterial infec- tions were randomly divided into cefepime and ceftazidime groups and received therapeutic,to e- valate by pharmacoeconomic cost-effectiveness analysis.Results:Clinical cure rates and total ef- fective rates were 72.3%,92.3% in the cefepime group,and 68.8%,90.6% in the ceftazidime group respectively,and cefepime's cost/effect was lower thean ceftazidime's in the treatment of lower respiratory tract infection(LRTI),urinary tract infection (UTI),peritonitis,hepato-bil- iary infection and septicemia.Conclusion:Cefepime is better than ceftazidime in the treatment of LRTI,UTI,peritonitis,hepato-biliary infection and septicemia caused by sensitive pathogens, and is a good cost-effect drug.
出处
《黑龙江医药》
CAS
2001年第6期452-454,共3页
Heilongjiang Medicine journal
