摘要
用正交试验法以藏药复方挥发油中桂皮醛为指标成分 ,挥发油包结的收得率 ,桂皮醛包合率 ,挥发油总合率为指标考察赛朱复方中挥发油的β 环糊精包合工艺。结论 :实验研究以 β CD与水的比例为 1∶10 ,挥发油 β CD的比例为 1ml∶10g ,在35℃下包结 1h为最佳工艺条件。经GC MC分析 ,证明包结前后挥发油主要成分基本一致 ,β 环糊精能有效的保存挥发油的有效成分。经红外光谱分析 ,挥发油包合物明显比不包合的挥发油稳定 ,整个包合物主要呈现 β CD的红外光谱图谱。
Objective:To optimize techniques of volatile oil Saizhu prescription,a Tibet drug,parceled with β cyclodextrin(β CD).Methods:The processes of cinnamic aldehyde and total volatile oil parceled with β CD were optimized by the enwraped ratio as markers with orthogonal design method.Results and Conclusion:The best technical conditions were:β CD∶water=1∶10,volatile oil∶β CD=1ml∶10g,stirred for 1 hour at 35℃.The main components of volatile oil between unparceled and parceled with β CD were unchanged by GC\|MS analysis.The stability of volatile oil parceled β CD was better than that of unparceled by IR spectra.
出处
《中国实验方剂学杂志》
CAS
2002年第2期3-5,共3页
Chinese Journal of Experimental Traditional Medical Formulae
关键词
Β-环糊精
桂皮醛
正交试验
气质联用
中药
Cyclodextrin
cinnamic aldeyde
Orthogonal design method
GC\|MS analysis
