摘要
目的研究分析妇科腹腔镜手术麻醉不同剂量舒芬太尼应用情况。方法 127例采用腹腔镜手术治疗的患者,根据舒芬太尼麻醉剂量不同分为A组(64例)和B组(63例)。A组舒芬太尼剂量为0.3 mg/L, B组舒芬太尼剂量为0.5 mg/L。比较两组患者术后不同时间段疼痛评分、镇痛泵药物使用剂量、自主呼吸时间、拔管时间以及术后不良反应发生比较。结果 B组患者术后2、4、12 h疼痛评分均低于A组,差异具有统计学意义(P<0.05)。A组患者不良反应发生率为7.81%,低于B组的20.63%,差异具有统计学意义(P<0.05)。A组患者自主呼吸时间、拔管时间均短于B组,但差异具有统计学意义(P>0.05)。A组术后2 h镇痛泵药物使用剂量为(10.08±0.75)ml,术后4 h为(21.01±1.02)ml,术后12 h为(55.97±5.18)ml;B组术后2 h镇痛泵药物使用剂量为(9.03±0.26)ml,术后4 h为(17.86±0.74)ml,术后12 h为(47.19±4.63)ml;B组患者术后2、4、12 h镇痛泵药物使用剂量均低于A组,差异具有统计学意义(P<0.05)。结论妇科腹腔镜手术麻醉舒芬太尼剂量的增加使镇痛效果明显提高,术后镇痛泵药物使用剂量较低,但是术后不良反应发生率也随之增加,所以临床舒芬太尼剂量使用应根据患者的实际情况进行剂量的选择。
Objective To study and analyze the application of different doses of sufentanil in gynecological laparoscopic surgery. Methods A total of 127 patients treated with laparoscopic surgery were divided by different doses of sufentanil into group A(64 cases) and group B(63 cases). Group A was treated with 0.3 mg/L of sufentanil, and group B was treated with 0.5 mg/L of sufentanil. Comparison were made on pain scores at different time points after operation analgesic pump dosage, spontaneous breathing time and extubation time and occurrence of postoperative adverse reactions between the two groups. Results Group B had lower pain score at 2, 4 and 12 h after operation than group A, and the difference was statistically significant(P<0.05). Group A had lower incidence of adverse reactions as 7.81% than 20.63% in group B, and the difference was statistically significant(P<0.05). Group A had shorter spontaneous breathing time and extubation time than group B, but the difference was not statistically significant(P>0.05). Group A had dosage of analgesic pump as(10.08±0.75) ml at 2 h after operation,(21.01±1.02) ml at 4 h after operation and(55.97±5.18) ml at 12 h after operation, which were(9.03±0.26),(17.86±0.74) and(47.19±4.63) ml in group B. Group B had less dosage of analgesic pump at 2, 4 and 12 h after operation than group A, and the difference was statistically significant(P<0.05). Conclusion The increase of sufentanil dosage in gynecological laparoscopic surgery can significantly improve the analgesic effect and lower the dosage of analgesic pump after operation. However, the incidence of adverse reactions after operation also increased, so the clinical dosage of sufentanil should be selected according to the actual situation of patients.
作者
魏成敏
WEI Cheng-min(Department of Anesthesia,Yanggu County People's Hospital,Liaocheng 252300,China)
出处
《中国实用医药》
2018年第34期10-12,共3页
China Practical Medicine
关键词
妇科腹腔镜
麻醉
不同剂量舒芬太尼
研究
Gynecological laparoscope
Anesthesia
Different doses of sufentanil
Research
