期刊文献+

利妥昔单抗致肠梗阻不良反应1例 被引量:2

原文传递
导出
摘要 利妥昔单抗(rituximab,RTx)是一种人-鼠嵌合性抗B淋巴细胞表面CD20抗原的单克隆抗体,是FDA批准的首个用于治疗肿瘤的单克隆抗体[1-2]。近年来,利妥昔单抗的应用范围不断扩大,在器官移植中的应用也越来越广泛,但利妥昔单抗导致的不良反应也逐渐增多[2-4]。我院1例肝移植患儿首次应用利妥昔单抗治疗时出现肠梗阻的严重不良反应,现报道如下。
出处 《中国医院药学杂志》 CAS 北大核心 2018年第22期2384-2385,共2页 Chinese Journal of Hospital Pharmacy
基金 北京医卫健康公益基金会医学科学研究基金资助项目(编号:YWJKJJHKYJJ-B16244) 天津市卫计委科技基金(编号:2015KY09)
  • 相关文献

参考文献2

二级参考文献41

  • 1Lim I.C, Koh LP, Tan P. Fatal cytokine release syndrome with chimeric anti-CD20 monoclonal antibody rituximab in a 71-year-old patient with chronic lymphocytic leukemia[J]. J Clin Oncol, 1999, 17(6): 1962-3.
  • 2Reports of Bowel Obstruction and Gastrointestinal Perforation with RITUXAN (rituximah)[EB/OL].[2008-4- 28] http://www.hc-sc.gc.ca/dhp-mps/medeff/advisoriesavis/prof/_2006/rituxan 3 hpc-cps-eng.php, http://www. hc -sc.gc.ca/dhp -mps/medeff/advisories -avis/pro f/_2006/ fituxan_3_hpc-eps-eng.php.
  • 3Carson KR, Evens AM, Richey EA, et al. Progressive multifocal leukoencephalopathy after rituximab therapy in HIV-negative patients: a report of 57 cases from the Research on Adverse Drug Events and Reports project[J]. Blood, 2009, 113(20): 4834-40.
  • 4National Cancer Institule. Common Terminology Criteria for Adverse Events v3.0. (CTCAE)[EB/OL]. 2006-07-07 [2006-08-09]. http://ctep.cancer.gov/fonns/CTC AEv3.pdf.
  • 5Vogel WH. Infusion reactions: diagnosis, assessment, and management[J]. Clin J Otwol Nurs, 2010, 14(2): 10-21.
  • 6Lenz HJ. Management and preparedness for infusion and hypersensitivity reactions [J]. Oncologist, 2007, 12 (5): 601-9.
  • 7Lanini S, Molloy AC, Fine PE, et al. Risk of infection in patients with lymphoma receiving rituximab: system- atic review and meta-analysis [J]. BMC Med, 2011, 12 (9): 36-50.
  • 8Diaz-Lagares C, Perez-Alvarez R, Garcia-Hernandez FJ, et al. Rates of, and risk factors for, severe infections in patients with systemic autoimmune diseases receiving biological agents off-label [J]. Arthritis Res Ther, 2011, 13(4): R112.
  • 9Spina M, Jaeger U, Sparano infusional cyclophosphamide JA, et al. Rituximab plus doxorubicin, and etoposide in HIV -associated non -Hodgkin lymphoma: pooled results from 3 phase 2 trials [J]. Blood, 2005, 105(5): 1891-7.
  • 10Pei SN, Chen CH, lee CM, et al. Reactivation of hepatitis B virus following rituximab-based regimens: a serious complication in both HBsAg-positive and HBsAgnegative patients[J]. Ann Hematol, 2010, 89(3): 255-62.

共引文献17

同被引文献16

引证文献2

二级引证文献4

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部