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雷替曲塞联合顺铂对晚期食管癌患者进行化疗的效果及安全性分析 被引量:2

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摘要 目的 :研究用雷替曲塞联合顺铂对晚期食管癌患者进行化疗的效果及安全性。方法 :选取南通大学附属海安人民医院肿瘤科收治的65例晚期食管癌患者作为研究对象。将其中使用氟尿嘧啶联合顺铂进行化疗的32例患者设为对照组,将其中使用雷替曲塞联合顺铂进行化疗的33例患者设为观察组。比较接受化疗后两组患者的近期疗效和发生不良反应的情况。结果 :接受化疗后,观察组患者的RR和DCR均高于对照组患者,P<0.05。在用药期间,观察组患者恶心呕吐的发生率和Ⅲ级、Ⅳ级骨髓抑制的发生率均低于对照组患者,P <0.05。结论 :用雷替曲塞联合顺铂对晚期食管癌患者进行化疗的近期疗效较为理想,且用药的安全性较高。
出处 《当代医药论丛》 2018年第23期131-133,共3页
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