摘要
多囊卵巢综合征(PCOS)是一种常见的生殖内分泌代谢性疾病,合并胰岛素抵抗(IR)的PCOS患者约占50%~70%。临床研究报道PCOS患者合并存在VD缺乏为普遍现象,且PCOS患者胰岛素抵抗(IR)与维生素D(VD)缺乏存在相关性。越来越多证据显示VD缺乏与PCOS-IR之间存在一定的关系,且对多囊卵巢综合征胰岛素抵抗发生、防治具有较深远的影响,但其发病机制尚未明确。多囊卵巢综合征伴胰岛素抵抗患者中医发病机制主要是肾脾功能失调,且维生素D的转化过程及作用机制与"肾藏精"的功能极为相似。文章通过"肾藏精"理论探讨VD缺乏与PCOS-IR的关系,藉此为中西医结合防治PCOS-IR提更多的参考方向。
Polycystic ovary syndrome(PCOS)is a common reproductive endocrine metabolic disease,50%-70% of PCOS patients combined insulin resistance(IR).The study found that there was a lack of VD in PCOS,and the insulin resistance(IR)of PCOS patients was related to the deficiency of vitamin D in serum,and had a profound effect on the incidence and prevention of insulin resistance in polycystic ovary syndrome.This paper discusses the relationship between VD and PCOS-IR from the theory of"kidney essence",and provides new ideas for treating PCOS-IR in combination with Chinese and western medicine.
作者
车日文
李双蕾
蒋云霞
贾慧敏
万亚宁
CHE Riwen;LI Shuanglei;JIANG Yunxia;JIA Huimin;WAN Yaning(Guangxi University of Chinese Medicine, Guangxi Nanning 530001, China;The First Affiliated Hospital of Guangxi University of Chinese Medicine, Guangxi Nanning 530023, China)
出处
《中医药临床杂志》
2018年第12期2204-2207,共4页
Clinical Journal of Traditional Chinese Medicine
基金
广西名老中医民族医传承工作室建设项目
桂卫中[2014]9号
关键词
多囊卵巢综合征
胰岛素抵抗
维生素D
肾藏精
Polycystic ovary syndrome
Insulin resistance
Vitamin D
Kidney storing essence