摘要
目的:系统评价吴茱萸穴位贴敷联合基础降压药对高血压的治疗效果。方法:检索从建库至2017年7月Pubmed、CNKI、维普、万方数据库中收载的吴茱萸穴位贴敷联合基础降压药为干预措施治疗高血压随机对照试验(RCT),按照纳入与排除标准独立筛选文献,提取资料并进行质量评价后采用RevMan5.3软件进行Meta分析。结果:经筛选最终纳入9篇文献共733例受试者,Meta分析结果显示与对照组比较,吴茱萸穴位贴敷联合基础降压药物降压总体疗效较好,差异有统计学意义。结论:基于目前的临床证据,在常规基础降压药治疗的基础上联用吴茱萸穴位贴敷治疗高血压可以提高疗效,但由于纳入的研究质量和数量有限,尚需更多高质量、大样本的随机双盲对照试验加以确证。
Objective:Systematic evaluation of therapeutic effect of Acupoint sticking of Fructus Evodiae on hypertension. Methods:Randomized controlled trials(RCTs) concerning fructus evodiae and basic therapy for hypertension were searched through databases such as PubMed CNKI, VIP, Wanfang from inception to July 2017. Literatures were extracted according to inclusion and exclusion criteria, and methodological quality of included studies was assessed.Meta-analysis was performed by RevMan 5.3. Results:After selection,9 randomized controlled trials were included,a total of 733 patients.The results showed that compared with the control group,there were significant differences in the treatment of hypertension. Conclusion:Actual clinical evidence indicates that on the basis medicine therapy, add Acupoint sticking of Fructus Evodiae can improve therapeutic efficacy.However, reliability of systematic review is affected by low quality and number of included studies. More large-scale RCTs should be carried out for further validation.
出处
《中国中医基础医学杂志》
CAS
CSCD
北大核心
2018年第12期1757-1761,共5页
JOURNAL OF BASIC CHINESE MEDICINE
基金
教育部"春晖计划"合作科研项目(Z2015005)-吴茱萸次碱黏胶分散型透皮贴剂研究
贵州省研究生卓越人才计划项目(黔教研合ZYRC字[2014]019)-贵州省药剂学研生卓越人才培养计划
贵州省中医药管理局科研课题(ZYY2013-94)-吴茱萸次碱黏胶分散型压敏胶贴剂的设计与评价
遵义医学院博士启动基金项目(遵医院办发[2013]69号)-吴茱萸总碱压敏胶贴剂研究
关键词
吴茱萸
穴住贴敷
高血压
META分析
Fructus Evodiae
Acupoint sticking
Hypertension
Meta-analysis
