摘要
目的探讨鼻咽癌患者发生营养不良的相关危险因素。方法回顾性分析了150例鼻咽癌患者的临床资料,根据营养评估结果将其分为营养不良组(n=105例)和对照组(n=45例),对可能影响营养不良的危险因素进行对比分析。以是否营养不良为因变量,纳入血清白蛋白水平(ALB)、血红蛋白(Hb)水平、年龄、病程、身高体重指数(BMI)、消化道症状等变量引入方程进行多因素Logistic回归分析。结果 150例患者中营养不良组105例,对照组45例。ALB <40(g/L)、Hb <110(g/L),年龄> 60岁,病程> 6个月,BMI <18. 5(kg/m^2),消化道症状数目> 3个,接受手术治疗与鼻咽癌患者放化疗期间营养不良的发生密切相关(P <0. 05)。结论 ALB <40(g/L)、Hb <110(g/L),年龄> 60岁,病程> 6个月,BMI <18. 5(kg/m^2),消化道症状数目> 3个,接受手术治疗是导致鼻咽癌患者放化疗期间发生营养不良的独立危险因素。
Objective To discuss the risk factors of malnutrition in nasopharyngeal carcinoma patients. Methods One hundred and fifty patients with nasopharyngeal carcinoma were retrospectively analyzed,according to whether exist malnutrition they were divided into malnutrition group( n = 105) and control group( n = 45). Taking malnutrition as the dependent variable,the multiple logistic regression analysis were performed when variables of albumin level( ALB),hemoglobin level( Hb),age,course of diseases,body mass index( BMI) and gastrointestinal symptoms were put into equation. Results Among the 150 cases,there were 105 cases occurred malnutrition( group malnutrition) and 45 cases had no malnutrition( control group). ALB < 40( g/L),Hb < 110( g/L),age > 60( year),course of diseases > 6( month),BMI < 18. 5( kg/m^2),gastrointestinal symptoms > 3( item) and accept surgery were closely related to malnutrition( P < 0. 05). Conclusion ALB < 40( g/L),Hb < 110( g/L),Age > 60( year),course of diseases > 6( month),BMI < 18. 5( kg/m^2),gastrointestinal symptoms > 3( item) and accept surgery are independent factors for the malnutrition in nasopharyngeal carcinoma patients.
作者
李欣
孙明贺
高媛
LI Xin;SUN Ming-he;GAO Yuan(Department of Head and Neck Radiotherapy,Cancer Hospital of Harbin Medical University, Harbin 150081,China)
出处
《哈尔滨医科大学学报》
CAS
2018年第5期465-468,共4页
Journal of Harbin Medical University
基金
国家自然科学基金资助项目(81802990)
关键词
鼻咽癌
放化疗
营养不良
营养支持治疗
nasopharyngeal carcinoma
radiotherapy and chemotherapy
malnutrition
nutritional support therapy
