摘要
目的探讨激素联合手术治疗肉芽肿性乳腺炎的临床效果。方法回顾性分析2015年1月至2017年12月在汕尾逸挥基金医院及中山大学孙逸仙纪念医院治疗的100例肉芽肿性乳腺炎患者的临床资料,根据治疗方式不同分为抗生素治疗组(20例)、激素治疗组(20例)、激素治疗+抗生素组(30例)及激素+手术治疗组(30例),比较不同组之间的治疗有效率和复发情况。结果激素+手术治疗组患者的治疗有效率为96.7%,明显高于其他各组,复发率为13.3%,明显低于其他各组,差异均有统计学意义(P<0.05);抗生素+激素治疗组患者的治疗有效率为76.7%,明显高于抗生素治疗组的40.0%和激素治疗组的55.0%,复发率为33.3%,明显低于抗生素治疗组的65.0%和激素治疗组的50.0%,差异均有统计学意义(P<0.05);抗生素治疗组和激素治疗组患者的治疗有效率和复发率间比较差异均无统计学意义(P>0.05);抗生素治疗组治疗有效率最低,复发率最高。结论激素联合手术治疗肉芽肿性乳腺炎临床效果明显,患者复发率低,值得在临床上推广应用。
Objective To explore the clinical effect of steroid therapy combined with surgery in the treatment of granulomatous mastitis. Methods The clinical data of 40 patients with granulomatous mastitis, who treated in Shanwei Yihui’s Funds Hospitals and Sun Yat-sen Memorial Hospital from Jan. 2015 to Dec. 2017, were retrospectively analyzed. According to different treatment methods, these patients were divided into the antibiotic treatment group(20 cases), steroid treatment group(20 cases), steroid + antibiotic treatment group(30 cases), and steroid + surgery treatment group(30 cases). The effectiveness and recurrence of treatment between different groups were observed. Results The effective rate of the steroid + surgery treatment group(96.7%) was significantly higher than that in the other groups;while the recurrence rate(13.3%) was significantly lower than that in the other groups(all P<0.05). The effective rate(76.7) of steroid + antibiotic treatment group was significantly higher than that of antibiotic treatment group(40.0%) and steroid treatment group(55.0%). The recurrence rate(33.3%) was significantly lower than that of the antibiotic treatment group(65.0%) and steroid treatment group(50.0%), P<0.05. There was no significant difference in the effective rate and recurrence rate between the antibiotic treatment group and the steroid treatment group(P>0.05). The antibiotic treatment group had the lowest effective rate and the highest recurrence rate. Conclusion Steroid therapy combined with surgery for granulomatous mastitis has obvious clinical effects, and the patient has a low recurrence rate, which is worthy of clinical application.
作者
黄汉扬
贾卫娟
黄静吟
万德炎
HUANG Han-yang;JIA Wei-juan;HUANG Jing-yin;WAN De-yan(Department of General Surgery,Shanwei Yihui's Funds Hospitals, Shanwei 516600,Guangdong,CHINA;Department of Breast Tumor Medicine,Sun Yat-sen Memorial Hospital,Sun Yat-sen University,Guangzhou 510000,Guangdong,CHINA)
出处
《海南医学》
CAS
2019年第1期81-83,共3页
Hainan Medical Journal
关键词
肉芽肿性乳腺炎
抗生素
激素
手术
疗效
Granulomatous mastitis
Antibiotics
Steroid
Surgery
Effect
