摘要
目的对比大动脉狭窄脑梗死患者应用介入术以及常规溶栓治疗的实际效果。方法选择2016年8月～2017年8月间在我院进行治疗的大动脉狭窄脑梗死患者共60例作为研究分析对象,使用随机数字法,将所有患者分为观察组、对照组两组,对照组进行常规静脉溶栓治疗,观察组在对照组的治疗基础上联合支架取栓介入术进行治疗,将两组患者的治疗总有效率、NIHSS评分改善率、mRS评分神经功能良好率、并发症出现情况以及患者死亡率进行对比。结果在治疗总有效率方面,观察组明显高于对照组(P <0.05);在NIHSS评分改善率、mRS评分神经功能良好率方面,观察组明显优于对照组(P <0.05);在并发症出现情况方面,观察组明显低于对照组(P <0.05);在患者死亡率方面,观察组明显低于对照组(P <0.05)。结论在治疗大动脉狭窄脑梗死患者中,应用静脉溶栓联合支架取栓介入术治疗的效果较为显著,出现并发症较少,安全性更高。
Objective To comparative clinical efficacy of interventional therapy and conventional thrombolytic therapy in the treatment of cerebral infarction patients with aortic stenosis.Methods A total of 60 patients with aortic stenosis and cerebral infarction who were treated in our hospital between August 2016 and August 2017 were selected as subjects for study analysis.All patients were divided into observation group and control group by random number method.The control group received conventional intravenous thrombolytic therapy.The observation group was treated with stent thrombectomy intervention based on the treatment of the control group.The total treatment efficiency,NIHSS score improvement rate,mRS score neurological function good rate,and complications of the two groups were evaluated.And patient mortality was compared.Results The total effective rate of treatment was significantly higher in the observation group than in the control group (P <0.05 ).The NIHSS score improvement rate and the mRS score neurological function rate were significantly better in the observation group than in the control group (P <0.05 ).The incidence of complications was significantly lower in the observation group than in the control group (P <0.05 ).In terms of patient mortality,the observation group was significantly lower than the control group (<0.05 ).Conclusion In the treatment of cerebral infarction with large artery stenosis,the use of intravenous thrombolytic therapy combined with stent thrombectomy intervention has a significant effect with fewer complications,higher safety.
作者
胡杨真
HU Yang-zhen(Guangdong Qingyuan People's Hospital,Qingyuan ,511500,China)
出处
《血栓与止血学》
2018年第6期909-911,共3页
Chinese Journal of Thrombosis and Hemostasis
关键词
大动脉狭窄
脑梗死
支架取栓介入术
常规静脉溶栓
Aortic stenosis
Cerebral infarction
Stent thrombectomy
Conventional intravenous thrombolysis
