摘要
目的 :探讨风湿热和幼年性类风湿性关节炎患儿血沉、C—反应蛋白与铜兰蛋白、触珠蛋白的关系及意义。方法 :采用免疫散射比浊法检测C—反应蛋白、铜兰蛋白、触珠蛋白 ,和血沉分析仪检测血沉 ,并与对照组 2 5例健康儿对比。结果 :结缔组织疾病患儿血沉、C—反应蛋白与铜兰蛋白、触珠蛋白均有不同程度的升高 ,2 5例健康儿童的检测结果均在正常范围之内 ,并且所有实验数据以均值±标准差 (x±s)表示 ,T检验作组间差异显著性检验 (P <0 .0 1)。用直线回归及其系数的显著性检验作相关分析 ,铜兰蛋白、触珠蛋白的水平与血沉、C—反应蛋白呈正相关 (P <0 .0 1)。结论 :在结缔组织疾病患儿中铜兰蛋白、触珠蛋白的测定与血沉、C—反应蛋白的作用相仿。
Objective: To explore the relationship and clinical significance of detection for erythrocyte sedimentation rate(ESR) , C-reactive protien (CRP) , ceruloplasmin (CER) and haptoglobin(HAP) in acute rheumatic fever(ARF) and jurenile rheumatoid arthrltis (JRA) .Methods : CRP, CER and HAP were tested respectively by imunonephelometry. ESR was tested by erythrocyte sedimentation analyzer. And compared with the control group of 25 health children. Results : All the contents of ESR , CRP , CER, HAP in children with connective tissue inflammatory diseases are elevated, but the contents of the control group are normal range, more ever all the records are indicated by mean value standard devlation(x±s) , T-test are used in different group by significance test (P<0.01) , Linear regression and coefficient with significance test are used in correlation analysis ,the level of CER,HAP and ESR,CRP offer positive correlation (P<0.01) .Conclusion: The action of determinations CER,HAP are similar to ESR,CPR in connective tissue inflammatory diseases .
出处
《河北医学》
CAS
2002年第3期195-196,共2页
Hebei Medicine
