期刊文献+

染色内镜和放大内镜技术是提高早期大肠癌诊治水平的重要手段 被引量:27

Chromoendoscopy and high-magnification colonoscopy in early detection of colorectal cancer JIANG Bo
在线阅读 下载PDF
导出
摘要 应用常规内镜技术难以发现大肠平坦型病变和凹陷型病变。近年来染色内镜和放大内镜技术已经发展成熟,在国外已获广泛应用,可以发现大肠微小病变和早期大肠癌。应用腺管开口分型方法可以预测肿瘤病变的组织学类型及肿瘤的浸润深度,据此可确定行内镜下粘膜剥离术或分片粘膜剥离术将肿瘤切除,抑或行外科手术治疗。在当前我国的胃肠内镜医疗界,应广泛开展染色内镜和放大内镜的临床应用,以早期发现大肠病变,提高我国大肠癌的内镜诊治水平。 Flat and depressed lesions in the colons are difficult to detect with conventional colonoscopic techniques, and chro-moendoscopy with high magnification has consequently gaincd wide application for early detection of colorectal cancer andits precursors. These techniques allow targeted in vivo luminal treamients and make possible earier and more accurate diagno-sis on the basis of pit pattem classification as proposed by Kudo Sinei. According to studies conducted by Japanese re-searchers, magnification chromoendoscopy can be used to assess the histology and invasive depth of the cancer, and thus helpin the detection of flat and depressed cokonic lesions and the subsequent surgical treatment of these lesions by way of endo-scopic mucosal resection (EMR) or endoscopic piecemeal mucosal resection (EPMR). Due attention should be given to theclinical significance of high-magnification chromoendoscopy in the identification of the lesions.
作者 姜泊
出处 《第一军医大学学报》 CSCD 北大核心 2002年第5期385-387,共3页 Journal of First Military Medical University
关键词 早期大肠癌 染色内镜 放大内镜 腺管开口类型 平坦病变 凹陷病变 early colorectal cancer chromoendoscopy magnify colonoscopy pit pattern flat lesion, depressed lesion
  • 相关文献

参考文献3

二级参考文献11

  • 1[1]Longacre TA, Fenoglio-Preiser CM. Mixed hyperplastic adenomatous polyps/serrated adenomas. A distinct form of colorectal neoplasia[J]. Am J Surg Pathol, 1990, 14(6): 524-37.
  • 2[2]Rubio CA, Rodensjo M. p53 overexpression in flat serrated adenomas and flat tubular adenomas of the colorectal mucosa[J]. J Cancer Res Clin Oncol, 1995, 121(9-10): 571-6.
  • 3[3]Makinen MJ, George SM, Jernvall P, et al. Colorectal carcinoma associated with serrated adenoma- prevalence, histological features,and prognosis[J]. J Pathol, 2001, 193(3): 286-94.
  • 4[4]Hiyama T. Yokozaki H, Shimamoto F, et al. Frequent p53 gene mutations in serrated adenomas of the colorectum [J]. J Pathol, 1998,186(2): 131-9.
  • 5[5]Veress B, Gabrielsson N, Granqvist S, et al. Mixed colorectal polyps.An immunohistologic and mucin-histochemical study [J]. Scand J Gastroenterol, 1991, 26( 10): 1049- 56.
  • 6[6]Fujishima N. Proliferative activity of mixed hyperplastic adenomatous polyp/serrated adenoma in the large intestinc, measured by PCNA (proliferating cell nuclear antigen) [J]. J Gastroenterol, 1996,31(2): 207-13.
  • 7[3]Kudo Sinea. Early colorectal cancer - detection of depressed types of colorectal carcinoma [M]. Tokyo: Igaku-Shoin Medical Publisher.1996. 50-1.
  • 8寺井毅,今井靖,二瓶英人,等.LSTの臨床的意義[J].早期大腸癌,1998,2(5):505-16.
  • 9[5]Longacre TA, Fenoglio-Preiser CM. Mixed hyperplastic adenomatous polyps/serrated adenomas. A distinct form of colorectal neoplasia[J]. Am J Surg Pathol, 1990, 14(6): 524-37.
  • 10[6]Fujishima N. Proliferative activity of mixed hyperplastic adenomatous polyp/serrated adenoma in the large intestine, measured by PCNA (proliferating cell nuclear antigen)[J ]. J Gastroenterol, 1996, 31(2): 207-13.

共引文献47

同被引文献203

引证文献27

二级引证文献203

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部