摘要
胆红素是铁卟啉化合物在人体内的代谢产物之一,主要来源于衰老红细胞崩解后的血红蛋白,随胆汁排泄。凡能引起胆红素的生成过多或使肝细胞对胆红紊的摄取、结合、排泄过程发生障碍的因素,都可使血中胆红素浓度增高,出现高胆红素血症。因此,测定血中胆红素水平对临床诊断肝胆疾病,溶血等有着重要的意义。
A bilirubin oxidase (EC 1.3.3.5) producing strain, Mv 2.1089, was isolated from several strains of Myrothecium verrucaria by dilution method. The optimum conditions of enzyme production were investigated and the results were as follows: the suitable medium was cultured at 25℃ on a rotatiag shaker glucose and peptone, at pH 6.0. The strain was cvltured at 25℃ on a rotating shaker (150 r/min) for 96 h. Bilirubin oxidase with 0.5—1.5 u/ml was obtained in the culture medium.
出处
《微生物学报》
CAS
CSCD
北大核心
1991年第2期156-159,共4页
Acta Microbiologica Sinica
关键词
胆红素氧化酶
产酶菌
分离
Bilirubin oxidase
Myrothecium verrucaria
