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血清单胺氧化酶测定的意义及其局限性 被引量:11

The Diagnostic Value and Limitations of Serum Monoaminoxdase Examination
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摘要 目的 探讨空腹血清单胺氧化酶 (MAO)的检测在肝病患者诊断中的应用价值。方法 收集 6 2 7例临床资料 ,用 SPSS软件及四格表法进行统计分析。结果 正常人 MAO为 2 2 .8U± 10 .8U,肝病组 MAO显著高于正常人和非肝病组 (P<0 .0 1) ;肝硬化患者 MAO为 78.8U± 30 .9U,与其他各组相比差异有显著性 (P<0 .0 1) ;亚急性重型肝炎和慢性重型肝炎的 MAO分别为 5 7.4 U± 14 .9U和 5 8.9U± 16 .8U,与其他肝炎各组相比差异有显著性 (P<0 .0 1)。结论  MAO是反映肝脏纤维化活动程度的敏感指标 ,对肝硬化。 Objective To discuss the diagnostic value of the examination of serum monoaminoxdase (MAO) in patients suffering from liver diseases.Methods Clinical data of 627 cases were statistically analyzed with SPSS for window and other statistical procedures reported previously.Results The mean value of MAO in healthy subjects was 22.8 U±10.8 U,and the MAO level in liver disease groups was significantly higher than that in other groups(P<0.01).The mean of MAO of the patients with liver cirrhosis was 78.8 U±30.9 U,significanthy higher than that in other groups;The mean value of MAO of patients with severe subacute hepatitis and.Severe chronic hepatitis were 57.4 U±14.9 U and 58.9 U±16.8 U respectively,significantly higher than those in other hepatitis groups (P<0.01).Conlusions MAO was a valuable marker reflecting the severity of liver hepatofibrosis and MAO was valuable for diagnosis of liver cirrhosis?severe subacute hepatitis and severe chronichep atitis.
出处 《中国误诊学杂志》 CAS 2002年第6期836-838,共3页 Chinese Journal of Misdiagnostics
关键词 肝硬化 诊断 肝炎 单胺氧化酶 血压 血清学检验 Liver cirrhosis/diagnosis Hepatitis/diagnosis Monoamine oxidase/blood
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  • 1林果为.诊断性试验的研究与评价[A].陈敏章.中华内科学 第1版[C].北京:人民卫生出版社,1999.904—913.
  • 2Obata K,Wata T,Tnouek T,et al.One step sandwich enzyme immunoassay for human type Ⅳ collgen using monodonal antibodies clin dim.Acta,1989,181:293
  • 3骆抗先.肝纤维化的血清学诊断[J].临床肝胆病杂志,1996,12(1):1-2. 被引量:36

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