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妊娠合并自身免疫性甲状腺疾病患者检测甲状腺功能的价值 被引量:6

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摘要 目的:检验妊娠合并自身免疫性甲状腺病( AITD)患者的有关指标,为孕妇进行常规甲状腺功能检查提供依据。方法将孕妇127例按甲状腺病变情况分为4组:Graves病( GD)患者30例,桥本甲状腺炎( HT)患者31例, AITD病史28例,健康孕妇38例;分别在孕早期(孕16~20周)和孕晚期(孕32~40周)用化学发光法检测4组孕妇血TSH、FT4、FT3、TGAb、TPOAb、TRAb等指标;用酶联免疫吸附试验检测白细胞介素-17水平。结果孕早期及孕晚期检验结果均显示GD组、HT组、病史组TGAb、TPOAb、TRAb、IL-17水平均明显升高( P均<0.01),与健康组比较差异均有统计学意义( P均<0.01)。结论妊娠合并AITD患者的TGAb、TPOAb、TRAb、IL-17显著升高,疑似患有AITD及有既往病史的孕妇在妊娠前及妊娠期常规进行甲状腺功能及IL-17水平检测。
出处 《现代中西医结合杂志》 CAS 2014年第23期2560-2562,共3页 Modern Journal of Integrated Traditional Chinese and Western Medicine
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参考文献15

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二级参考文献75

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同被引文献45

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