摘要
目的探讨不同肠道准备方法对肠道手术肠管清洁效果与切口细菌状况的影响。方法将60只实验大鼠采用随机数字表法分为三组各20只,分别采用50%硫酸镁导泻联合0.1%肥皂水灌肠法(A组)、聚乙二醇电解质散剂灌胃(B组)、甘露醇灌胃(C组)进行术前肠道准备。结果术中三组都观察到结肠内空虚、清洁、管腔塌陷。A组细菌计数(3 220.0±311.2)个、B组细菌数(2 224.0±347.8)个、C组细菌数(2 524.0±296.7)个;A组肠道术口细菌数显著高于B组及C组(均P<0.01),而B组与C组术口细菌数比较,差异无统计学意义(P>0.05)。结论聚乙二醇电解质散剂和甘露醇灌胃顺行清洁肠道,对清除肠腔细菌效果好于硫酸镁导泻联合肥皂水灌肠。
Objective To study the effect of different bowel preparation methods on the intestinal cleaning and bacteria growth at the incision.Methods Totally 60 experimental rats were divided randomly into 3 groups of 20,and received preoperative bowel preparation with a combination of 50％ magnesium sulfate and 0.1 ％ soapsuds （group A）,polyethylene glycol electrolyte powder （group B） or mannitol （group C） respectively.Results The colon was observed empty,clean and of collapse in the three groups.Besides,the bacteria count at the incision was （3 220.0±311.2）,（2 224.0±347.8）and （2 524.0±296.7） for group A,B and C respectively,with that of group A significantly higher than that of group B and C （P＜0.01 for both）,and no significant difference between group B and C （P＞0.05）.Conclusion The bowel preparation with polyethylene glycol electrolyte powder or mannitol is more effective than combination of 50％ magnesium sulfate and 0.1％ soapsuds in cleaning intestinal bacteria.
关键词
肠道准备
清洁灌肠
聚乙二醇电解质散剂
甘露醇
动物实验
intestinal preparation
clean enema
polyethylene glycol electrolyte
mannitol
animal experiment
