摘要
目的探讨咪达唑仑静脉麻醉对老年骨科患者术后谵妄(EA)的影响效果。方法选取2011年4月—2013年10月本科择期行骨科手术的108例患者,随机分为咪达唑仑静脉麻醉组(观察组)和丙泊酚组(对照组),观察两组患者的麻醉及手术时间以及术中及术后不良反应情况,采用智能精神状态检查量表(MMSE)评价认知功能。结果观察组苏醒时间、丙泊酚用量、术后恶心呕吐(PONV)以及术后EA的发生率低于对照组,差异有统计学意义(P<0.05)。结论咪达唑仑作为麻醉诱导用药可以减少丙泊酚的用量,可以减少对心血管的影响,可使老年骨科患者较快苏醒,且对于术后EA发生率影响不明显。
Objective To discuss effect of midazolam intravenous anesthesia on elderly patients＇ postoperative delirium in orthopedics department. Methods 108 cases patients in our department who took orthopedic operation in different time from April 2011 to October 2013,were randomly divided into midazolam intravenous anesthesia group（ observation group） and propofol group（ control group）. Two group patients＇ anesthesia and operation time,the adverse reactions of intraoperation and after operation were observed,cognitive function was evaluated by MMSE scale. Results Observation group＇ s revival time,dosage of propofol,incidence rate of PONV,EA were shorter than control group,the differences were statistically significant（ P〈0. 05）. Conclusion Midazolam as anesthesia induction drug can reduce the dosage of propofol and the influence on cardiovascular,intravenous anesthesia rapidly effective,it could make elderly patients in orthopedics department rapid recovery,reduced non- incidence rate of postoperative delirium.
出处
《临床合理用药杂志》
2014年第21期9-10,12,共3页
Chinese Journal of Clinical Rational Drug Use
关键词
咪达唑仑
老年
医院
骨科
谵妄
Midazolam
Aged
Hospitals
osteopathic
Delirium
