摘要
目的探讨米氮平对偏头痛的临床疗效。方法选取2012年6月-2013年6月在盐城市第一人民医院心理门诊就诊的偏头痛患者共80例,均符合《国际头痛分类与诊断标准(第2版)》(ICHD-II),按随机数字表法分为观察组和对照组各40例。两组患者在统一运用神经科常用药物的基础上,观察组加用抗抑郁药米氮平,疗程4周。所有患者分别于治疗前和治疗4周末各进行一次焦虑自评量表(SAS)、抑郁自评量表(SDS)测评;评估偏头痛患者头痛症状的严重程度。结果米氮平治疗4周后,研究组SAS、SDS评分与对照组相比差异有统计学意义(P均<0.01)。观察组和对照组偏头痛总有效率分别为90.00%、72.50%,差异有统计学意义(P<0.05)。结论米氮平能改善偏头痛患者焦虑、抑郁情绪,减轻偏头痛患者的临床症状。
Objective To observe the clinical Effects of combined anti - depression medicine therapy on anxiety and depression syndromes seen on migraine patients. Methods Divide 80 migraine patients into two groups randomly, observation group （ n = 40） and control group （n = 40）. Both groups of patients are given common neurological drugs, but only patients in observation group are treated with extra small doses of mirtazapine for four weeks. All patients are assessed by SAS and SDS before and at the end of the treatment. The assessment of clinical effects are conducted through observing the changes in the scale of headache suffered by patients. Results Standard Value Change of the SAS and SDS results of observation group before and at the end of the treatment showed obvious statistic variations （P 〈0.01 ）. The total effectiveness rate of the observation group stands at 90.00% higher than the 72.50% of the control group, which represents obvious variations （ P 〈 0.05 ）. Conclusion Using anti - depression drugs can have distinct amelioration on migraine patients＂ anxiety and depression symptoms and can mitigate the clinical symptoms of migraine.
出处
《四川精神卫生》
2014年第3期260-261,共2页
Sichuan Mental Health
关键词
偏头痛
米氮平
焦虑
抑郁
Migraine
Mirtazapine
Anxiety
Depression
