摘要
目的评估新辅助化疗治疗浸润性乳腺癌后,实施保乳术合并即刻假体重建术后的短期并发症。方法对48例进行新辅助化疗的患者与162例未进行术前化疗的患者,进行保留皮肤的乳腺切除术合并即刻乳房重建的术后并发症的对比评估。结果新辅助治疗组术后短期并发症的整体发生率显著少于对照组(14%vs 29%,P=0.036),但假体挛缩率并无降低(8%vs 13%,P=0.452)。结论新辅助化疗在保乳术合并即刻乳房重建术后并未增加短期术后并发症,该联合疗法可为年轻女性患者的治疗提供方向。
[Objective] To access the influence of the short-term complication of the neoadjuvant chemotherapy for invasive breast cancer which after skin sparing mastectomy and immediate prosthetic reconstruction. [Method] Make a comparison between 48 patients treated with neoadjuvant chemotherapy and 162 contrast patients to access the surgical complications of skin sparing mastectomy and immediate prosthetic reconstruction. [Results] The overall short-term postoperation complications of the neoadjuvant chemotherapy group was significantly less than the control group （14% vs 29%; P=0.036）, while the variance of loss of pros- theses is not significant. [Conclusion] The overall short-term complications of the neoadjuvant chemotherapy treated patients was significantly less than the controls, and such combined therapy may offer new orientation to treat these young female.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2014年第23期67-70,共4页
China Journal of Modern Medicine
关键词
新辅助化疗
即刻乳房重建
保留皮肤乳腺切除术
术后并发症
浸润性乳腺癌
neoadjuvant chemotherapy
immediate prosthetic reconstruction
skin sparing mastectomy
surgical complications
invasive breast cancer
