摘要
目的探讨胃肠癌患者血清性激素水平及其临床意义。方法采用放射免疫法,测定122例胃癌患者血清黄体生成素(LH)、卵泡刺激素(FSH)、催乳素(PRL)、睾酮(T)及雌二醇(E2)水平。结果胃癌患者E2、T水平与正常对照组比较显著下降(P<0.05),女性患者E2水平下降更为明显(P<0.01);PLR、LH及FSH水平男性患者与对照组比较,差异无统计学意义(P>0.05),女性患者PRL水平显著高于对照组(P<0.01)。E2、T水平随胃癌分期表现为I期>II期>III期>IV期,I期较III期、IV期差异有统计学意义(P<0.05)。结论胃癌患者血清性激素水平变化检测结果可指导判断病情与发展预后。
Objective To study the clinical significance of serum sexual hormones level determination in gastric cancer pa- tients. Methods Serum levels of LH, FSH, PRL, T and E2 were determined by RIA in 122 patients with gastric cancer. Re- suits Serum levels of T and E2 in gastric cancer patients were significantly lower than the normal control group （ P 〈 0.05 ） , especially the serum E2 level in female patients （ P 〈 0.01 ）. The serum levels of PLR, LH and FSH showed no significant differences between male patients and normal control group, while PRL level of female gastric cancer patients was significantly higher than that in the normal control group（P 〈0. 01 ）. Serum levels of T and E2 gradually dropped in stage Ⅰ, Ⅱ, Ⅲ, IV of gastric carcinoma in turn, and those in stage I were significantly higher than stage III and IV（P 〈 0.05）. Conclusion Serum sexual hormones level detection could help to evaluate the condition and prognosis of gastric cancer patients.
出处
《中国卫生检验杂志》
北大核心
2014年第16期2359-2360,共2页
Chinese Journal of Health Laboratory Technology
关键词
胃癌
性激素
放射免疫法
临床意义
Gastric cancer
Sexual hormone
Radioimmunoassay （RIA）
Clinical significance
