摘要
目的分析新疆伊犁地区哈萨克族与汉族冠心病患者冠状动脉粥样硬化斑块的双源CT特征,比较两民族间的差异。方法搜集自2011年6月至2012年12月在本院行双源CT冠状动脉造影检查（CTA）确诊为冠心病的哈萨克族患者185例,按性别比例及不同年龄段分层随机抽取同期汉族患者185例,分析冠状动脉斑块成分、部位、血管狭窄程度及累及冠状动脉的分支数,并进行比较。结果 （1）哈萨克族和汉族患者冠状动脉粥样硬化斑块发生均以前降支多发,其次是右冠状动脉、左回旋支,左主干最低。两民族斑块成分比较,均以非钙化斑块（NCAP）为主,哈萨克族NCAP构成比高于汉族（P〈0.05）。（2）哈萨克族女性NCAP构成比高于汉族女性（P〈0.05）,斑块引起管腔重度狭窄比例高于汉族女性（P〈0.05）。（3）按年龄段分组,在40~49岁年龄段哈萨克族斑块发生率低于汉族（P〈0.05）;50~59岁年龄段哈萨克族NCAP构成比高,钙化斑块（CAP）构成比低于汉族（P〈0.05）;≥70岁年龄段哈萨克CAP的构成比低,管腔中度狭窄的比例低于汉族（P〈0.05）。结论哈萨克族和汉族冠状动脉粥样硬化斑块特征存在差异,哈萨克族总体NCAP构成比高于汉族;哈萨克族女性NCAP构成比高于汉族女性,病变程度高于汉族女性。提示临床工作中对哈萨克族NCAP的一级预防显得尤其重要。
Objective To analyzed the characteristics of coronary atherosclerotic plaque in Kazak nationality patients and Han nationality patients with coronary heart disease （CHD） in Yili Kazak Autonomous Prefecture, and to compare the imaging features between the two groups. Methods During the period from June 2011 to December 2012, 185 Kazak pa- tients with coronary heart disease （study group） were treated at author＇s hospital. Dual source CT coronary angiography was carried out in all the 185 patients. According to the sex ratio and different age group, 185 Hart nationality CHD pa- tients were randomly selected and used as the control group. The composition and location of plaque, severity of artery ste- nosis, and the number of involved coronary artery branches were determined, and the results were compared between the two groups. Results （ 1 ） In both groups, the atherosclerotic plaque incidence of LAD was highest, followed by, in a de- scending order, RCA, LCX and LMA. Non-calcification atherosclerotic plaque （NCAP） was most common in both groups, although the composition ratio of NCAP of the study group was higher than that of the control group （ P 〈 0.05 ）. （2） For female patients, the composition ratio of NCAP of the study group was higher than that of the control group （ P 〈 0.05 ）. The arterial stenosis caused by atherosclerotic plaque in the study group was more severe than that in the control group （P 〈 0.05 ）. （3） In age group of 40 -49 years, the incidence of atherosclerotic plaque in the study group was lower than that in the control group （ P 〈 0.05 ）. In age group of 50 - 59 years, the composition ratio of NCAP of the study group was high- er than that of the control group （P 〈0.05）. In age group of ~70 years, the composition ratio of calcification atheroscle-rotic plaque in the study group was lower than that in the control group, and the incidence of moderate arterial stenosis in the study group was lower than that in the control group （ P 〈 0.05 ）. Conclusion Differences in the characteristics of coronary atheroselerotic plaque exist between Kazak nationality patients and Han nationality patients. The composition ratio of NCAP is higher in Kazak patients than that in Han patients. The composition ratio of NCAP is higher in Kazak female patients than that in Han female patients, and the atherosclerotic lesion is more severe in Kazak female patients than that in Han female patients. Therefore, the prevention of NCAP for Kazak nationality patients is particularly important in clinical practice.
出处
《临床放射学杂志》
CSCD
北大核心
2014年第9期1343-1348,共6页
Journal of Clinical Radiology
基金
新疆乌鲁木齐市科学计划项目(编号:Y121320019)
关键词
冠心病
双源CT
哈萨克族
汉族
Coronary artery disease Dual source CT Kazak nationality Han nationality
